Suppression

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suppression

[sə′presh·ən]
(computer science)
Removal or deletion usually of insignificant digits in a number, especially zero suppression.
Optional function in either on-line or off-line printing devices that permits them to ignore certain characters or groups of characters which may be transmitted through them.
(electronics)
Elimination of any component of an emission, as a particular frequency or group of frequencies in an audio-frequency of a radio-frequency signal.

Suppression

 

in genetics, a phenomenon that prevents the appearance of a character resulting from mutation and that causes partial or complete restoration of the normal phenotype.

Intragenic suppression is caused by a second (suppressor) mutation in the same gene in which the first (direct) mutation occurred. Intergenic suppression is caused by a second mutation in other genes that are located at a considerable distance from the suppressed gene. In intragenic suppression, a protein coded by a given gene can reacquire functional activity, although its original structure, in contrast to true reverse mutation, or reversion, is not restored. In intergenic suppression, the normal phenotype may be restored in some cases owing to mutations that permit other means of metabolism which do not require the functioning of the given gene. In other cases, the normal phenotype may be restored as a result of mutations that alter the process by which the genetic information of the mutant gene is realized.

The phenomenon of suppression, first discovered in 1920 by the American geneticist A. H. Sturtevant, is used to study the genetic code and other aspects of molecular genetics.

REFERENCE

Stent, G. Molekuliarnaia genetika. Moscow, 1974. Chapter 6. (Translated from English.)

I. I. TOLSTORUKOV

References in periodicals archive ?
The most common adverse effect was appetite suppression, which occurred less frequently with the 75-mg dosage than with the 150-mg dosage.
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Dr Karen Ersche, from the Behavioural and Clinical Neuroscience Institute at the University of Cambridge, said that their findings challenged the widely held assumptions that cocaine use leads to weight loss through appetite suppression and suggested profound metabolic alteration that needs to be taken into account during treatment.
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No category is more faddish than appetite suppression," says one chain drug category manager.
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While the munchies triggered by smoking marijuana provide a rich vein of humor for comedians, the appetite suppression brought about by cocaine abuse is no laughing matter.
has introduced Trim Again whey protein, which combines the weight loss benefits of whey protein with the appetite suppression and body fat reduction benefits of two popular herbal ingredients.
Dieters sometimes need a little extra kick in the form of a weight-control supplement to help them with appetite suppression, water weight gain, cortisol reduction or metabolism boosting.
A 4-week, double-blind, crossover study of four doses (placebo, 18 mg, 36 mg, or 54 mg of daily Concerta) in 27 children found linear dose response effects for appetite suppression, stomachaches, and daytime tiredness.
The slimming was so dramatic that the group suspected more than appetite suppression was involved.