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McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Assessment of heart rate variability in Boxers with arrhythmogenic right ventricular cardiomyopathy. Journal of the American Veterinary Medical Association, v.224, p.534-535, 2004.
Usefulness of immunostaining for plakoglobin as a diagnostic marker of arrhythmogenic right ventricular cardiomyopathy. Am J Cardiol.
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet 2004; 36 : 1162-4.
The gene for arrhythmogenic right ventricular cardiomyopathy maps to chromosome 14q23-q24.
Electrocardiographic features of arrhythmic syncope * Non-sustained VT * Bifascicular block (LBBB or RBBB combined with left anterior or left posterior fascicular block) or other intraventricular conduction delay with QRS >120 ms * Sinus bradycardia (<50 bpm or sinoatrial block in absence of negative chronotropic medications or physical training) * Pre-excited QRS complex * Prolonged or shortened QT interval * RBBB pattern with ST elevation in V1--V3 (Brugada pattern) * Negative T waves in the right praecordial leads, epsilon waves, and ventricular late potentials suggestive of ARVC ARVC = arrhythmogenic right ventricular cardiomyopathy; LBBB = left bundle branch block; RBBB = right bundle branch block; VT = ventricular tachycardia.
A postmortem examination revealed the teenager unknowingly had Arrhythmogenic Right Ventricular Cardiomyopathy, when the heart muscle changes into fat and stops it beating properly.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by progressive fatty or fibrofatty infiltration of the right ventricular myocardium, which constitutes a substrate for electrical instability and a focus of ventricular arrhythmias (1).
MIAMI -- Arrhythmogenic right ventricular cardiomyopathy is a diagnostically challenging condition that is often overlooked as the cause of sudden cardiac death in athletes.
The second most common cause of unexpected sudden death in the young is Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), where the normal right ventricular muscle cells are replaced by fibrous tissue and fat.
Nadia, a staff nurse, learned earlier this week that she has arrhythmogenic right ventricular cardiomyopathy - the same form of the disease as experts believe her brother Jamie died from.
There are four known separate and distinct conditions of cardiomyopathy - arrhythmogenic right ventricular cardiomyopathy, dilated cardiomyopathy, hypertrophic cardiomyopathy and restrictive cardiomyopathy.

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