(redirected from Arterial thrombosis)
Also found in: Dictionary, Thesaurus, Medical.


thrombosis (thrŏmbōˈsĭs), obstruction of an artery or vein by a blood clot (thrombus). Arterial thrombosis is generally more serious because the supply of oxygen and nutrition to an area of the body is halted. Thrombosis of one of the arteries leading to the heart (heart attack; see infarction) or of the brain (stroke) can result in death and, in a vessel of the extremities, may be followed by gangrene. Acute arterial thrombosis often results from the deposition of atherosclerotic material in the wall of an artery, which gradually narrows the channel, precipitating clot formation (see arteriosclerosis). A thrombus that breaks off and circulates through the bloodstream is called an embolus.
The Columbia Electronic Encyclopedia™ Copyright © 2022, Columbia University Press. Licensed from Columbia University Press. All rights reserved.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



the formation of blood clots during life in the lumen of a blood vessel or in the heart.

Thrombogenesis is promoted by injury to the vascular wall owing to atherosclerosis or inflammation, by the slowing of the blood flow, and by an increase in the coagulability and viscosity of the blood. Peripheral venous thrombosis is most common; thrombosis in the arterial system occurs less frequently. Arterial thrombosis interferes with the blood supply to areas of tissue and often leads to necrosis of such tissue. For example, coronary thrombosis results in myocardial infarction, and cerebral thrombosis, in a stroke, or cerebrovascular accident. The thrombus may subsequently either dissolve (undergo lysis), with partial or complete restoration of the blood vessel’s patency, or it may become thickened (organized). Multiple capillary thrombosis, a syndrome involving disseminated intravascular blood coagulation, is often combined with an increased tendency for tissues to bleed. The condition may develop during shock, hemorrhage, or severe infectious diseases, or it may be a manifestation of intolerance for drugs.

Biochemical and roentgenological methods of examination are used to diagnose thrombosis. Treatment includes the administration of anticoagulants, antispasmodics, and fibrinolytic and anti-inflammatory agents, as well as surgical removal of the thrombus.


Machabeli, M. S. Koagulopaticheskie sindromy. Moscow, 1970.
Kuznik, B. I., and V. P. Skipetrov. Formennye elementy krovi, sosudistaia stenka, gemostaz i tromboz. Moscow, 1974.
Raby, C. Lokalizovannaia i rasseiannaia vnutrisosudistaia koaguliatsiia. Moscow, 1974. (Translated from French.)
Quick, A. J. Hemorrhagic Diseases and Thrombosis, 2nd ed. Philadelphia, Pa., 1966.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Formation of a thrombus.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.


1. the formation or presence of a thrombus
2. Informal short for coronary thrombosis
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
In accordance with previous findings, the concentration and prevalence of LA and aCL were significantly higher in the patients with arterial thrombosis, venous thrombosis, or thrombocytopenia than in those without complications (21-23).
Although previous studies have emphasized that 89% of cases of neonatal thrombosis are related with catheters, new studies show an association with catheters with a rate of 54% in venous thrombosis and with a rate of 27% in arterial thrombosis (34).
Considering the fact that the adverse pregnancy outcomes in younger age is associated with an arterial thrombosis in an unusual site which could not be explained by the prothrombotic state of the pregnancy alone favours a strong clinical suspicion towards APS.
In her medical history, there were two risk factors for an arterial thrombosis: drospirenone-containing oral contraceptive use and the prothrombin G20210A mutation.
Recent studies show that arterial thrombosis occurs more frequently than previously thought.
In this study, we show that Apocynin treatment, by preventing ROS generation, restores the physiological megakaryopoiesis and platelet function and reduces arterial thrombosis. Overall, these findings suggest that ROS play a key role in the susceptibility to thrombosis induced by chronic psychological/behavioral stress, affecting the production/activation of megakaryocytes, with consequent increase of both number and reactivity of circulating platelets.
Deficiency of both protein C and S may result in increased risk of venous and arterial thrombosis [1].
[40] showed that hypercoagulable patients with arterial thrombosis or VTE, pregnancy complications, or autoimmune diseases have increased fibrin generation and reduced fibrinolysis.
[sup][3] Embolic arterial occlusion is the cause of acute ischemia in 15% of patients, and arterial thrombosis is the cause in 85% of patients, most of whom have atherosclerotic disease.