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painful inflammation of a joint or joints of the body, usually producing heat and redness. There are many kinds of arthritis. In its various forms, arthritis disables more people than any other chronic disorder. The condition can be brought about by nerve impairment, increased or decreased function of the endocrine glands, or degeneration due to age. Less frequently, it is caused by infection (tuberculosistuberculosis
(TB), contagious, wasting disease caused by any of several mycobacteria. The most common form of the disease is tuberculosis of the lungs (pulmonary consumption, or phthisis), but the intestines, bones and joints, the skin, and the genitourinary, lymphatic, and
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, gonorrheagonorrhea
, common infectious disease caused by a bacterium (Neisseria gonorrhoeae), involving chiefly the mucous membranes of the genitourinary tract. It may occasionally spread to membranes in other parts of the body, especially those of the joints and the eyes.
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, Lyme diseaseLyme disease
or Lyme borreliosis,
a nonfatal bacterial infection that causes symptoms ranging from fever and headache to a painful swelling of the joints. The first American case of Lyme's characteristic rash was documented in 1970 and the disease was first identified
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, rheumatic feverrheumatic fever
, systemic inflammatory disease, extremely variable in its manifestation, severity, duration, and aftereffects. It is frequently followed by serious heart disease, especially when there are repeated attacks. Rheumatic fever usually affects children.
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Rheumatoid arthritis, an autoimmune diseaseautoimmune disease,
any of a number of abnormal conditions caused when the body produces antibodies to its own substances. In rheumatoid arthritis, a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individual's own gamma globulin
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 of unknown cause, is the most crippling form. Women are much more susceptible to it than men. Although rheumatoid arthritis usually appears between the ages of 25 and 50, it also occurs in children. Osteoarthritis, the most common type, occurs usually in people over 50. It tends to be more severe when the joints have been strained by obesity or overwork. Goutgout,
condition that manifests itself as recurrent attacks of acute arthritis, which may become chronic and deforming. It results from deposits of uric acid crystals in connective tissue or joints.
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, the third most common form of arthritis, affects men almost exclusively.

Symptomatic treatment for arthritis includes use of heat, physical therapy, and nonsteroidal anti-inflammatory drugsnonsteroidal anti-inflammatory drug,
a drug that suppresses inflammation in a manner similar to steroids, but without the side effects of steroids; commonly referred to by the acronym NSAID .
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 such as a cox-2 inhibitor (Celebrex), aspirinaspirin,
acetyl derivative of salicylic acid (see salicylate) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic fever and
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, ibuprofenibuprofen
, nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxen and ketoprofen, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967.
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, and naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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. Remission of symptoms can sometimes be achieved with methotrexate, gold salts, penicillamine, and short-term cortisonecortisone
, steroid hormone whose main physiological effect is on carbohydrate metabolism. It is synthesized from cholesterol in the outer layer, or cortex, of the adrenal gland under the stimulation of adrenocorticotropic hormone (ACTH).
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, but they often have undesirable side effects. Orthopedic surgery, including artificial joint implantation, may be done in severe cases.



a group of joint diseases that are of infectious origin or arise as a result of disruption of the nutrition of the joint. Arthritis can be an independent disease or a manifestation of some other disease. Symptoms that may indicate arthritis include pain, redness, swelling, deformation, impaired joint function, increase of local (cutaneous) temperature above the joint, and fever. In different forms of the disease the symptoms appear in various combinations.

The Ninth International Congress of Rheumatologists in 1957 accepted a working classification and nomenclature of joint diseases; this was reflected in the classification and terminology of joint diseases developed in the USSR in the same year. The classification was based on etiological (causal), pathogenetic (according to the mechanism of evolution), and clinical-anatomical principles. The disease of one joint is monoarthritis; of several joints, polyarthritis. Arthritis can be acute and chronic, with or without effusion (serous, suppurative, or hemorrhagic). According to its origin, arthritis is divided into traumatic, infectious, degenerative, arthritis associated with other diseases, and rare forms of joint lesions. The infectious forms of arthritis include rheumatic fever (Sokol’skii-Bouillaud’s disease); arthritis associated with the presence in the organism of one or another specific infection, such as tuberculous, syphilitic, dysenteric, gonorrheal, septic, and brucellosis arthritis; infectious nonspecific arthritis; and ankylosing spondylitis (von Bechterew-Strumpell’s disease). Degenerative arthritis arises as a result of metabolic disturbance and includes gouty arthritis, arthritis accompanying Kashin-Beck disease and hemophilia, rheumatoid arthritis, degenerative (hypertrophic) arthritis (osteoarthritis), and arthritis resulting from changes in the endocrine system (climacteric, thyrotoxic, and so on). This group also includes arthritis associated with vitamin deficiency (scorbutic arthritis), physical over-exertion, chilling, and unsanitary conditions at home and on the job (arthritis in miners, transport workers, and metallurgical workers). Traumatic arthritis includes arthritis occurring after open (penetrating) or closed joint injury, as well as in cases of repeated mild traumatism (vibration arthritis). Arthritis can also be associated with diseases such as systemic lupus erythematosus, periarteritis nodosa, leukemia and other blood diseases, psoriasis, and diseases of the nervous system.

In some cases arthritis progresses with little change in the joints; in other cases there is significant change in the synovial sheath, cartilage, bone, and joint capsule and ligaments. Arthritis can terminate in complete restoration of normal joint function, but it can also lead to disfigurement of the joint and its partial or complete immobilization.

Treatment consists of isolation of the factor causing arthritis or treatment of the disease that caused its development. Depending on the character of the arthritis, antibiotics, hormone preparations, anti-inflammatory and analgesic drugs, physiotherapy, or therapeutic gymnastics are prescribed. Surgical treatment is widely used; this consists of resection of the capsule, arthroplasty, arthrotomy, and arthrodesis. Treatment is also carried out at health resorts (including Tskhaltubo, Piatigorsk, Saki, and Evpatoriia in the USSR).

In the prevention of arthritis, sanitation measures for work and daily life are very significant. These measures include improvement of working methods, labor protection, safety technology, elimination or lessening of professional hazards, and observation of hygiene in dwellings and dress.


Kushelovskii, B. P., M. A. Lasinovskii, and S. M. Ryss. Bolezni sustavov. Revmatizm. Avitaminozy. Moscow, 1961. (Bibliography.)
Leporskii, A. A. Lechebnaia fizicheskaia kul’tura pri bolezniakh obmena veshchestv i zabolevaniiakh sustavov. Moscow, 1960.
Nesterov, A. I., and Ia. A. Sigidin. Klinika kollagenovykh boleznei, 2nd ed. Moscow, 1966.


Any inflammatory process affecting joints or their component tissues.


inflammation of a joint or joints characterized by pain and stiffness of the affected parts, caused by gout, rheumatic fever, etc.
References in periodicals archive ?
Tambien habla sobre el anticuerpo monoclonal biologico Risankizumab que trata la psoriasis, y esta evaluado tambien para la enfermedad de Crohn y la artritis psoriasica.
De hecho en un estudio, 20 pacientes de 50, cumplieron los criterios de clasificacion de una enfermedad autoinmune como lupus eritematoso generalizado (LEG), artritis reumatoide (AR), esclerosis sistemica, sindromes de sobreposicion, anemia hemolitica, tiroiditis autoinmune, hepatitis autoinmune y colitis ulcerativa.
El caso corresponde a una mujer de 63 anos de edad, quien consulta por un cuadro de 3 meses de evolucion de poliartralgias de caracteristicas infamatorias y rigidez matutina de 40 minutos con antecedentes de artritis reumatoide desde hace 5 anos.
El virus de la artritis encefalitis viral caprina (AEVC) no esta difundido en rebanos de caprinos criados en forma semiextensiva y trashumante en cuatro provincias del departamento de Lima.
Midified disease activity scores the include twenty eitht joint counts development and validation ina preospective olgitudinal study of patients with rheumatoid artritis.
Busqueda e identificacion de los estudios: se hizo una busqueda por sensibilidad de la literatura relacionada con CVRS en AR en las bases de datos Pubmed, Science direct, Lilacs y Scielo-, se utilizaron las estrategias de busqueda Quality of life & rheumatoid arthritis, Calidad de vida & artritis reumatoide y Qualidade de vida & artrite reumatoide.
Al comparar con las patologias especificas se encontraron diferencias significativas entre los promedios (p<0,001) y fueron mayores los valores de la densitometria al comparar entre el grupo control con LES (p<0, 001, test de comparaciones multiples de Tamanhe), con escleroderma (p<0, 001, test de comparaciones multiples de Tamanhe) y con artritis (p<0,001, test de comparaciones multiples de Tamanhe) (tabla 1).
La enfermedad reumatica que predomino en el estudio fue la artritis reumatoide, siendo el tiempo trascurrido desde el diagnostico de once anos, con un rango de entre 1 a 30 anos.
Los sintomas de la artritis asociada al SS son: artralgias, especialmente en dedos, munecas y pies; inflamacion articular, muchas veces en forma simultanea y parestesia en articulaciones, sobre todo en la manana con duracion de una hora aproximadamente, (1,10) fenomeno de Raynaud, especialmente cuando hace frio y rash cutaneo, esencialmente agravado por la exposicion al sol y acompanado de alopecia.
La artritis se presenta predominantemente en rodillas u otras articulaciones grandes, en forma de mono u oligoartritis, con sinovitis y dolor, se ha asociado a infeccion por borrelia senso stricto y en estudios realizados en los Estados Unidos de America se aprecio que en un grupo de 21 pacientes seguidos durante 4 anos quienes no recibieron antimicrobianos se presento Artritis de Lyme en un periodo promedio de 43 meses (rango entre 4-76 meses).
Estas complicaciones afectan la calidad de vida y el estado de salud de estas personas, lo cual conduce a que se aumente el numero de medicamentos prescritos, ya no solo para tratar la artritis si no tambien los efectos adversos.
Fiel a su oficio, Nostradamus predijo su propia muerte, causada por la artritis y la gota.