protease

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protease

[′prōd·ē‚ās]
(cell and molecular biology)
An enzyme that digests proteins.
References in periodicals archive ?
(2016) Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.
Cold-adapted digestive aspartic protease of the clawed lobsters Homarus americanus and Homarus gammarus: biochemical characterization.
The active site lies between the identical subunits and has the characteristic Asp-Thr-Gly (Asp25, Thr26, and Gly27) sequence common to aspartic proteases. The two-subunit chains assemble to form a long tunnel covered by two flexible protein "flaps" which move a distance of up to 7 A when the enzyme becomes associated with a substrate [10].
Mechanism of Action of Aspartic Protease. Aspartic proteases (EC 3.4.23) are peptidases that exhibit various activities and specificities.
glabrata to produce proteases (aspartic protease and caseinase), phospholipase, esterase, phytase, hemolysin, and catalase were evaluated.
Human immuno-deficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease. Proc Natl Acad Sci USA 1989;86(6):1841-1845.
A study by Baeza et al has identified an aspartic protease, a protein of ~33 kDa to render X.
Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas.
Designing a drug that could selectively inhibit BACE1 could avoid the unwanted side-effects of also inhibiting other aspartic protease family members including BACE2.
A new class of inhibitors for the malarial aspartic protease plasmepsin II based on a central 11-azatricyclo[6.2.1.0 (2), (7)]undeca-2,4,6-triene scaffold.
Antimalarial synergy of cysteine and aspartic protease inhibitors.
The aspartic protease pepsin (up to 62.5 U [mL.sup.-1]) had no effect on the antimicrobial activity of either tachyplesin or pleurocidin against V.