protease

(redirected from Aspartic protease)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

protease

[′prōd·ē‚ās]
(cell and molecular biology)
An enzyme that digests proteins.
Mentioned in ?
References in periodicals archive ?
(2016) Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.
Transcriptional regulation of the 26S proteasome by Nrf1
Cold-adapted digestive aspartic protease of the clawed lobsters Homarus americanus and Homarus gammarus: biochemical characterization.
Partial biochemical characterization of digestive proteases present in the gastric juices of two Chilean crustaceans, Lithodes santolla (Molina, 1782) and Cancer edwardsii (Bell, 1835)
The active site lies between the identical subunits and has the characteristic Asp-Thr-Gly (Asp25, Thr26, and Gly27) sequence common to aspartic proteases. The two-subunit chains assemble to form a long tunnel covered by two flexible protein "flaps" which move a distance of up to 7 A when the enzyme becomes associated with a substrate [10].
Applications of Click Chemistry in the Development of HIV Protease Inhibitors
Mechanism of Action of Aspartic Protease. Aspartic proteases (EC 3.4.23) are peptidases that exhibit various activities and specificities.
The Role of Microbial Aspartic Protease Enzyme in Food and Beverage Industries
glabrata to produce proteases (aspartic protease and caseinase), phospholipase, esterase, phytase, hemolysin, and catalase were evaluated.
Relationship between the Antifungal Susceptibility Profile and the Production of Virulence-Related Hydrolytic Enzymes in Brazilian Clinical Strains of Candida glabrata
Human immuno-deficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease. Proc Natl Acad Sci USA 1989;86(6):1841-1845.
Cloning and expression of soluble recombinant HIV-1 CRF35 protease-HP thioredoxin fusion protein
A study by Baeza et al has identified an aspartic protease, a protein of ~33 kDa to render X.
Xanthophyllomyces dendrorhous as a new source of enzymes and its enzymatic potential in non-carotenoid related applications
Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas.
Polyclonal Napsin A Expression: A Potential Diagnostic Pitfall in Distinguishing Primary From Metastatic Mucinous Tumors in the Lung
Designing a drug that could selectively inhibit BACE1 could avoid the unwanted side-effects of also inhibiting other aspartic protease family members including BACE2.
Amino acid sequence and structural comparison of BACE1 and BACE2 using evolutionary trace method
A new class of inhibitors for the malarial aspartic protease plasmepsin II based on a central 11-azatricyclo[6.2.1.0 (2), (7)]undeca-2,4,6-triene scaffold.
Busqueda de nuevos agentes antiprotozoarios selectivos
Antimalarial synergy of cysteine and aspartic protease inhibitors.
Antimalarial activity of anthothecol derived from Khaya anthotheca (Meliaceae)
The aspartic protease pepsin (up to 62.5 U [mL.sup.-1]) had no effect on the antimicrobial activity of either tachyplesin or pleurocidin against V.
Antimicrobial peptides for use in oyster aquaculture: effect on pathogens, commensals, and eukaryotic expression systems

Encyclopedia browser ?
Full browser ?