atheroma

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atheroma

[‚ath·ə′rōm·ə]
(medicine)
A lipid deposit in the inner wall of an artery; characteristic of atherosclerosis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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The present study analyzed adult individuals of both genders, Afro-descendants, with cardiovascular risk factors, inhabitants of Quilombola remnant communities, and found no evidence of an independent association between serum levels of 25(OH)D and C-IMT, as well as the presence of carotid atheromatous plaques. On the other hand, an independent inverse association between 25(OH)D levels and urinary albumin excretion, assessed by ACR in an isolated urine sample, was observed.
By means of the software aid, we measured at the ascending portion of aorta the external elastic lamina perimeter (PE); the internal elastic lamina perimeter (PI); the area of the middle layer (AM); potential lumen of the vessel (LP), vessel lumen without the plaque; the real lumen of the vessel (LR), vessel lumen with the plaque; the area of atheromatous plaque (AP); and the percentage of vessel obstruction (% Obs).
Indeed, evidence has suggested that CRP may only potentiate vulnerability of the atheromatous plaque and formation of thrombi, rather than participate in the buildup of atheromas per se [11], highlighting the need for further research on CRP.
A major feature of this process is lipid accumulation, and the atheromatous plaque can become covered with a fibrous cap over the focal necrotic area in the later stages of this process.
Synthesis of TNF alpha and TGF beta mRNA in the different micro-environments within atheromatous plaques. Cardiovasc Res 1996; 32:1123-1130.
This case challenges the current conceptions of psittacine atherosclerosis in that peripheral arterial lesions were widespread and caused clinical signs, coronary atherosclerotic lesions and arterial atherothrombotic lesions were present, and histopathologic features were similar to those reported in other species--that is, lesions were principally localized in the tunica intima and its periphery and were characterized by atheromatous plaques with an abundance of macrophage foam cells and extracellular lipids.
Another positive effect of EDTA for the treatment of atherosclerosis, CAD, CVD and CVA is its ability to reduce or eradicate stenosis due to atheromatous plaques. Studies have found that chronic exposure to low levels of lead may contribute to hypertension and the development of CVD.
Data suggest that TNF antagonists might stabilize atheromatous plaques, while other results have shown improved flow-mediated vasodilation and endothelial function associated with TNF antagonists, the researchers said.
Because the increase in PAPP-A occurred within a few minutes after intravenous heparin injection, PAPP-A might be released from the vasculature with atheromatous plaques. Free PAPP-A is the major form of the PAPP-A increasing in the circulation (4), but only the surface-bound PAPP-A is active (3).
Chlamydia pneumoniae (now renamed Chlamydophila pneumoniae) (1) was detected in coronary atheromatous plaques in early 1990s suggesting an aetiological association (2).
These unstable atheromatous plaques have three histologic components: a large lipid core, many inflammatory cells, and a thin fibrous cap.