Perkin Reaction

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Perkin reaction

[′pər·kən rē‚ak·shən]
(organic chemistry)
The formation of unsaturated cinnamic-type acids by the condensation of aromatic aldehydes with fatty acids in the presence of acetic anhydride.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Perkin Reaction


a method of synthesizing β-arylacrylic acids (cinnamic acid and its derivatives and analogues) by reacting aromatic aldehydes with carboxylic acid anhydrides in the presence of a basic catalyst, such as alkali salts of carboxylic acids, carbonates of alkali metals, or tertiary amines:

The reaction was discovered by W. H. Perkin the Elder in 1868. It is widely used in organic chemistry. The synthesis of coumarin from salicylaldehyde and acetic anhydride is of commercial importance.


Organicheskie reaktsii, collection 1. Moscow, 1948. Page 267. (Translated from English.)
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.