azole

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Related to Azoles: Allylamines

azole

[′ā‚zōl]
(organic chemistry)
One of a class of organic compounds with a five-membered N-heterocycle containing two double bonds; an example is 1,2,4-triazole.
References in periodicals archive ?
Physicians can use pharmacokinetic profiles to choose among different statins and azoles to help avoid a drug interaction (table 26'71019).
Some studies have attributed resistance in Aspergillus partially to use of azole antifungal agents in agriculture.
Although this inverse relationship has been previously reported, (5,7,27,28) targeted deletion of ERG3 or ERG11 in Candida albicans and Candida glabrata seems to be a potential mechanism that may lead to increased susceptibility to AMB with increased resistance to azoles.
In a further analysis that controlled for confounding by underlying disease (vaginal candidiasis), pregnancies exposed to oral fluconazole were at significantly higher risk of spontaneous abortion, compared with pregnancies exposed to topical azoles (HR, 1.
In addition, the patients informed if they had been previously exposed to azoles at least once in the last year as treatment for VVC.
Among the azoles, the highest susceptibility was seen towards fluconazole followed by voriconazole and the least was towards ketoconazole.
Se observo una buena tolerancia a azoles y respuesta clinica.
In such cases, an azole cream is the better treatment choice, because azoles will kill Candida, bacteria, and dermatophytes that are there, she said.
The Infectious Diseases Society of America made no preference and recommends both local azoles and oral fluconazole (10).
A review of randomised control studies found allylamines were effective in curing fungal infections and produced a faster response than azoles but cure rates were similar.
pachydermatis is most susceptible to topical azoles like Miconazole, Ketoconazole and Clotrimazole (Outerbridge 2006).
For treatment of coccidioidomycosis, as well as fungi and molds (particularly Candida, Cryptococcus, and Aspergillus), there has been some evidence that there is antagonism between lipophilic azoles and amphotericin in vitro; however, this has not been proven in clinical trials.