GAD is an intracellular enzyme that catalyses the conversion of glutamic acid to the inhibitory neurotransmitter GABA (aminobutyric acid) and thus it is not normally expressed on the surface of the b-cell
. There are two major isoforms of GAD, i.e.
However, monoclonal B-cell
lymphocytosis (MBL) in patients with autoimmune diseases has rarely been reported.
Until now, formation of new B-cell
follicles in the lymph nodes was thought to only happen just after birth.
Due to their differing actions, B-cells
and their secreted antibodies are essential for the destruction of pathogens that occur outside body cells, while killer T-cells are needed to combat intracellular pathogens, including many viruses.
The small clonal B-cells
populations have been detected in myelodysplastic syndrome, post chemotherapy and benign disorders such as immune related or isolated thrombocytopenia, chronic obstructive pulmonary disease, and chronic cardiovascular disease (11) and in 1% of cases will be precursor of B-cell
We detected an unexpected Class II IgG complement-dependent cytotoxicity for all sera tested, enhanced by DTT treatment according to the ASHI scoring system (1 and 2 as negative, 4 as 30-49%, 6 as 50-79%, and 8 as 80-100% lysed lymphocytes (see Table 1)) and also in the B-cells
negative control well (serum pool from donors which shows no cytotoxic reactions in the lymphocytotoxicity test, BioRad, CA).
1) while the decrease in GSH level of B-cells
GSH was 2.019 M (32.41%), 1.917 M (35.82%), 1.650 M (44.76%), 1.478 M (50.52%), 1.408 M (52.86%) and 1.357M (54.57%) by all the six used concentrations of mercuric chloride with respect to B-cells
, and NK-cells were defined as described above, except for the omission of CD203A staining.
Serum immunoglobulin refers to a group of serum molecules produced by B-lymphocytes they are soluble and are secreted from B-cell
receptors and are produced to a maximum level to counter the invasion by an antigen and hence they are also called antibodies (Ismail and Asad 2009).
Remarkable Lack of Connections Involving B-Cells
Is Observed in Infants with Active Retinochoroidal Lesions.
To elucidate the role of intrahepatic B-cells
in the pathogenesis of chronic hepatitis B, we investigated the expression of CD20 marker on B-cells
in liver biopsy of these patients by immunohisto chemistry.
are the geek cells of our body -- super smart, they recognise bacteria through the "individual flags" they carry, the antigens on their surfaces, and can straightaway read if the flags signal danger.