Moreover, the analysis of drug response genomewide microarray data reveals that high doses of yohimbine can activate BAG6 in stage 1 bladder cancer, while high doses of chlorpromazine can activate HSPA5 and JUN in stage 4 bladder cancer.
Stage 1 bladder Stage 4 bladder cancer cancer The highly expressed ADRM1, COPS5, PSMD8, ADRM1, COPS5, PSMD8, genes for potential SUMO2, CALR, PDIA3, SUMO2, RNF126, CALR, inhibition strategy DNAJB11, HSPA5, RPN1, PDIA3, DNAJB11, of multiple drug CUL1, HSP90B1, KPNA2, HSPA5, RPN1, design PSMD12, ECT2, TK1, HSP90AA1, HSPA1B, TUBA1C, HN1, and ENO1 METTL23, RARRES3, KPNA2, PSMD12, ECT2, JUN, TK1, TUBA1C, HN1, and ENO1 The suppressed genes UBC, JUN, RARRES3, BCL3, FOS, UBC, and for potential and FOS GTF2A1 activation strategy of multiple drug design The BAG6, HUWE1, PAAF1, BAG6, HUWE1, PAAF1, nondifferentially PSMD10, FAF2, PCYT1A, PSMD10, FAF2, PCYT1A, expressed genes to and PSMD10 and PSMD10 avoid side-effect of multiple drug design The potential multiple drug combination
Recently, laparoscopic approach has been used for the management of mucocele of appendix, however care should be taken while retrieving the specimen to avoid spillage of contents by using endo bag6
. Irfan Skukar has described a case which presented with huge abdominal mass occupying almost whole of the abdominal cavity and constipation, an unusual presentation that was managed by laparotomy and excision of the mass signifying that it can grow to a very large size7.