BRCA gene

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Related to BRCA1: BRCA2

BRCA gene:

see breast cancerbreast cancer,
cancer that originates in the breast. Breast cancer is the second leading cause of cancer death in women (following lung cancer). Although the vast majority of the cases occur in women, some men also get breast cancer.
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References in periodicals archive ?
To test this idea, the scientists experimentally reduced BRCA1 levels in the neurons of mice.
Caption: All four of the rare aggressive uterine cancers occurred in the 296 women who had BRCA1 gene mutations.
There are also other types of cancer associated with a BRCA1 or BRCA2 mutation, including a significantly increased risk of ovarian cancer, prostate cancer, melanoma, and/or pancreatic cancer.
Every time I know or hear of a Jewish woman who developed breast cancer because of a BRCA1 or BRCA2 mutation, I think, "Why didn't we get the word out earlier?
Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype.
Mutations within BRCA1 and BRCA2 have been demonstrated to contribute to an increased risk of cancers other than breast and ovarian cancer.
Several approaches have been proposed to reclassify BRCA1 UVs into either disease-causing or neutral variants (1).
6,7,8) In fact, basal-like carcinomas include special morphologic types, such as metaplastic carcinomas, adenoid cystic carcinomas, carcinomas with medullary features, medullary carcinomas, and invasive carcinomas arising in the setting of BRCA1 mutations.
Attention, thus far, has been mostly focused on two high-risk predisposing genes: BRCA1 on the long arm of chromosome 17 [12] and BRCA2 [13] on the long arm of chromosome 13.
Louth, have now founded their own charity to help raise EUR40,000 to research the BRCA1 gene.
Although these findings provide some evidence of safety for hormone therapy in BRCA1 carriers, editorialists Dr.
Further, DHA supplementation increased levels of BRCA1 protein--the product of a major tumor-suppressor gene--by 60%.