Bacteria, Dissociation of

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Bacteria, Dissociation of

 

one of the manifestations of variability of microorganisms as a result of which bacteria that form large, smooth, shiny colonies on solid nutrient media and are usually designated as S forms (“smooth”) give rise to mutants or R forms (“rough”) that form dull, wrinkled colonies. Bacterial dissociation may occur spontaneously or under the influence of physical or chemical factors. Many physiological, biochemical, and immunological properties of a culture change in the course of bacterial dissociation. Therefore, the wrinkled forms of pathogenic bacteria are not used to make vaccines.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.