stratum germinativum
(redirected from Basal cell layer)Also found in: Dictionary, Thesaurus, Medical.
stratum germinativum
[′strad·əm ‚jər·mə·nə′tī·vəm] (histology)
The innermost germinative layer of the epidermis.
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In contrast to HGPIN, clear cell cribriform hyperplasia does not show any nuclear atypia, and a distinct basal cell layer is often visible in some of the glands.
In this study, we observed four cases of BPH (8%) that shin the presenting study, we observed four cases of BPH (8%) that showed p63 negativity and focal positivity for cyclin D1, that is, absence of basal cell layer [Table 1].
Malignant glands do not express GSTP1 at all, and they are completely negative due to the lack of the basal cell layer (Figures 1 and 2).
p53 expression above the basal cell layer in oral mucosa is an early event of malignant transformation and has predictive value for developing oral squamous cell carcinoma.
It takes about one month for skin cells to move from the basal cell layer to the top of the stratum corneum and slough off.
The scientists, led by Gary Halliday from the University of Sydney, wrote in the journal Proceedings of the National Academy of Sciences, 'The predominance of UVA mutations in the basal cell layer reinforces the pivotal role UVA may play in the malignant transformation of human skin.
This mixture of yeasts, hyphae, and matrix material is not seen when the organism is grown in liquid culture or on an agar surface, which suggests that morphogenesis is triggered when an organism contacts a surface and that the basal cell layer may have an important role in anchoring the biofilm to the surface (2,3,5,8).
This assumption is based on findings in the rabbit primary culture system which showed that for the urothelium to achieve maximal differentiation (from an undifferentiated basal cell layer to a high resistance apical umbrella cell layer) required growth of the cells on a permeable support, careful attention to seeding densities, and manipulation of the calcium concentration of the growth medium (29).
Approximately 3% of radiation below 300nm, 20% of radiation below 360nm and 33% of short visible radiation reaches the basal cell layer in non-tanned human skin.
Classically, they are thought to arise from epidermal basal cell layer, although current theory supports either a follicular or interfollicular stem cell origin.
In practical terms, IDC-P consists morphologically of a robust proliferation of prostatic adenocarcinoma cells within and expanding native, irregular, branched prostatic ducts with at least a partially intact basal cell layer.
CK5 helps to define the integrity of the basal cell layer, so the pathologist can confirm the existence of high-grade prostatic intraepithelial neoplasia (HGPIN); even if cancer is not found in the biopsy, ERG positive HGPIN gives strong support for the existence of prostate adenocarcinoma within a few millimeters of the biopsy due to a 'field affect.
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