base analog


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base analog

[′bās ′an·ə‚läg]
(cell and molecular biology)
A molecule similar enough to a purine or pyrimidine base to substitute for the normal bases, resulting in abnormal base pairing.
References in periodicals archive ?
We noticed that this clash could be eliminated by employing a five-membered ring base analog, in place of the six-membered F base.
23-26) However, another key point of Kool's discovery was that non-hydrogen-bonded hydrophobic base analogs could be potential candidates for creating unnatural third base pairs.
39,40) Replication experiments using base analogs proved the importance of these minor groove interactions.