The high-power field (HPF) examples for each category were controls (CTRL [A-D]), Becker muscular dystrophy
(BMD [E-H]), and Duchenne muscular dystrophy (DMD [I-L]).
Cardiac abnormalities in a follow-up study on carriers of Duchenne and Becker muscular dystrophy
Becker muscular dystrophy
severity is linked to the structure of dystrophin.
Table 1: Biochemical indices in the index case Biochemical indices Index BMD case References range CPK (U/L) 2461.00 38.00-174.00 Mb (ng/mL) 257.00 0.0-110.0 LDH (U/L) 518.24 135.00-225.00 CA (mg/dL) 8.18 8.10-10.0 CPK, creatine phosphokinase; Mb, myoglobin, LDH, lactate dehydrogenase; Ca, calcium; BMD, Becker muscular dystrophy
Abbreviations BMD: Becker muscular dystrophy
CCL: Beta-chemokine CXCL: Alpha-chemokine DMD: Duchenne muscular dystrophy GRMD: Golden retriever muscular dystrophy HFMD: Hypertrophic feline muscular dystrophy IIM: Idiopathic inflammatory myopathies IFN: Interferon IL: Interleukin TGF: Transforming growth factor TNF: Tumor necrosis factor.
Prenatal Diagnosis of Duchenne/ Becker muscular dystrophy
by short tandem repeat segregation analysis in Argentine families.
Muscular dystrophies encompass a diverse category of disease conditions with a broad spectrum of pathological outcomes, the most common disease manifestations being Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy
AND JASMIN, B.J., 2006.Utrophin upregulation for treating Duchenne or Becker muscular dystrophy
: how close are we?
The new short-term clinical trial will move the testing from animals to human patients with Becker muscular dystrophy
and examine the effects of acute tadalafil dosing on muscle blood flow during a bout of exercise.
Becker muscular dystrophy
is similar to DMD but has later onset and slower, more variable progression of symptoms.
Here we describe the generation of induced pluripotent stem (iPS) cells from patients with a variety of genetic diseases with either Mendelian or complex inheritance; these diseases include adenosine deaminase deficiency-related severe combined immunodeficiency (ADA-SCID), Shwachman-Bodian-Diamond syndrome (SBDS), Gaucher disease (GD) type III, Duchenne (DMD) and Becker muscular dystrophy
(BMD), Parkinson disease (PD), Huntington disease (HD), juvenile-onset, type 1 diabetes mellitus (JDM), Down syndrome (DS)/trisomy 21, and the carrier state of Lesch-Nyhan syndrome.
Steve Higginson, from Colwyn Bay, has struggled for many years to find appropriate care to treat his Becker muscular dystrophy
in what he says is a "desert" for patients like him.