Successful laparoscopic operation of bilateral pheochromocytoma in a patient with Beckwith-Wiedemann syndrome
Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome
Children born with Beckwith-Wiedemann syndrome
- named for the two doctors who discovered it - grow very large with big adrenal glands, elongated bones and oversized internal organs.
Genetic linkage of Beckwith-Wiedemann syndrome
A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome
Treatment of macroglossia in a child with Beckwith-Wiedemann syndrome
But 1,000 is too few to reveal increases in anomalies such as Beckwith-Wiedemann syndrome
, which normally occurs in only one in 15,000 births.
Diseases that cause enlargement of the tongue from multiple lesions include Down syndrome and rare conditions such as hypothyroidism, Beckwith-Wiedemann syndrome
, the mucopolysaccharidoses (MPS), multiple endocrine neoplasia syndrome type 2B (MEN 2B) and neurofibromatosis (von Recklinghausen's disease of the skin).
Among the unexplained, inherited abnormalities that Engel mentions as candidates are Beckwith-Wiedemann syndrome
, Miller-Dieker syndrome and Silver-Russell syndrome.
and Hemihyperplasia (Rosanna Weksberg, Cheryl Shuman, and Bruce Beckwith).
1) It can also occur in association with congenital syndromes like Kabuki make up syndrome, Beckwith-Wiedemann syndrome
, Poland syndrome, Jarcho Levin syndrome, infections like fetal rubella, cytomegalovirus infection, trisomies, chromosomal abnormalities, and other congenital anomalies like pulmonary hypoplasia, congenital heart disease, tracheomalacia, cerebral agenesis, renal ectopia, malrotation, deformities of pinna, Meckel's diverticulum and Werdnig Hoffman disease.
Pancreatoblastoma may occur sporadically or in association with genetic syndromes, such as Beckwith-Wiedemann syndrome
or familial adenomatous polyposis syndrome.