tolbutamide

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tolbutamide

[täl′byüd·ə‚mīd]
(pharmacology)
C12H18N2O3S A hypoglycemic drug effective when administered orally.
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References in periodicals archive ?
In general, CAB undergoes a two-electron change in its reactions forming the reduction products, benzenesulfonamide (BSA; PhS[O.sub.2]N[H.sub.2]) and NaCl.
The first-order dependence of rate on [[CAB].sub.o] and the addition of benzenesulfonamide ([PhSO.sub.2]N[H.sub.2]) having no effect on the reaction rate both indicate that PhS[O.sub.2]N[Cl.sub.2] and HOCl may not be the reactive species (4) and (6).
Hamed, Synthesis and In Vitro Anticancer Evaluation of Some Novel Hexahydroquinoline Derivatives Having a benzenesulfonamide Moiety, Eur.
N-Aralkylated-N-(2,4-dimethylphenyl) benzenesulfonamides (5a-e) projected structures were explicated by spectral analysis.
N-(5-Chloro-2-methoxyphenyl) -N-ethyl-4-chloro benzenesulfonamide (6b)
N-(5-Chloro-2-methoxyphenyl) -N-ethyl-2,3-dichloro benzenesulfonamide (6c)
This study pertains to novel synthesis of 4-(2-(2-hydroxybenzylideneamino) ethyl) benzenesulfonamide (a Schiff base) doped in xerogel silica, its characterization by FTIR, thermogravimetry, scanning electron micrography and porosimetry studies besides its application in adsorption of chromium (III) and lead (II) ions from aqueous media.
The ligand 4-(2-(2-hydroxybenzylideneamino) ethyl) benzenesulfonamide has many active sites for ion exchange or chelation with metal ions as shown in Fig.
McDonald et al., "Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis," Journal of Medicinal Chemistry, vol.
Lamas et al., "Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides," European Journal of Medicinal Chemistry, vol.