METHODS: Chiropractic and long acting beta agonists
were compared in non-pulmonary function measurements including quality of life scores and changes in rescue medication use.
The bronchodilating effect of a beta agonist
can be measured on the basis of airflow change, as indicated by, for example, a change in FEV1 or peak expiratory flow rate (PEFR).
Higher doses of corticosteroids do not improve symptoms for all patients and can have significant side effects, while long-acting beta agonists
have come under scrutiny for their risk of worsening asthma symptoms that could result in hospitalization and, rarely, death.
Although the risks of single-agent LABAs are well documented, in children and adults, there is not enough information to conclude that "use of the combination mitigates this risk that we know pertains to the long-acting beta agonists
Other outcomes included self-reports of morning and evening peak expiratory flow rate, daily use of beta agonists
, frequency of nocturnal awakenings, asthma-specific quality of life, as well as change in peripheral blood eosinophil counts.
Lemanske et al (10) performed a randomized, controlled trial in 175 adolescent and adult asthmatics to determine whether the addition of a long-acting beta agonist
might allow either elimination or dose reduction of inhaled corticosteroids.
Use beta agonist
inhalers as soon as wheezing or other EIA symptoms occur.
Supply medicament fixed combination corticosteroid / beta agonist
Anoro is a once-daily combination treatment comprised of two bronchodilators, umeclidinium (UMEC), a long-acting muscarinic antagonist (LAMA), and vilanterol (VI), a long-acting beta agonist
(LABA), in a single inhaler, the Ellipta.
In this clinical trial, zileuton CR demonstrated a significant reduction in the use of inhaled beta agonists
and provided early and sustained improvement in pulmonary function compared with placebo CR.
Brethine, is a very well established beta agonist
that fits nicely with our respiratory franchise.
Levalbuterol products will be complemented by our rapid-onset, long-acting beta agonist
R,R- eformoterol and our nonsedating antihistamine, norastemizole.