Chorionic Gonadotropin

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Related to Beta-HCG: BHCG

chorionic gonadotropin

[‚kȯr·ē′än·ik gō‚nad·ə′trō·pən]

Chorionic Gonadotropin

 

a hormone produced by the villi of the chorion and the placenta in some of the higher apes and in man. It is a complex protein (glycoprotein) containing the carbohydrates galactose (10.7 percent) and hexosamine (5.2 percent) and having a molecular weight of approximately 100,000. Chorionic gonadotropin has a stimulating effect on the corpus luteum, causing it to grow in size, increasing its secretory activity and prolonging its life; it converts the corpus luteum into the corpus luteum of pregnancy, which continues to secrete the hormone progesterone until the placenta is fully formed.

Chorionic gonadotropin, while similar in effect to the luteinizing hormone of the pituitary, differs from it in certain respects: it does not restore gonads atrophied after removal of the pituitary, it has no effect on avian gonads, and it causes only a slight enlargement of the ovaries in immature rodents.

References in periodicals archive ?
Combined, the ultrasound and beta-hCG results are 97%-100% sensitive and 95%-99% specific in diagnosing ectopic pregnancy.
The factors that favor conservative medical management are early diagnosis preferably before 12 weeks, low beta-hCG levels, and absence of cardiac activity [2,6].
After four cycles of chemotherapy, beta-hCG serum level decreased, but complete normalization was not obtained (serum level was 26vIU/L).
Makhijani and her coauthors included 398 patients whose medical histories allowed assessment of risk factors and whose record included at least two beta-HCG values taken 36-72 hours apart.
Patients with declining beta-hCG regularly followed up until their beta-hCG level was below 5 mIU/mL.
(b) Immunohistochemical stain for beta-hCG shows moderate to strong cytoplasmic staining of the syncytiotrophoblastic cells (x20).
Follow-up with serial Beta-hCG is crucial in managing these cases.
Serial serum beta-hCG levels after surgery showed a significant decline to 7 mU/mL 26 days later.
Naquelas pacientes com valores de beta-hCG entre 1.500 e 5.000 UI/ml e que preencham os demais criterios descritos, o tratamento medicamentoso tambem pode ser oferecido como opcao ao tratamento cirurgico, pois, embora estes valores apresentem taxas de falha e necessidade de intervencao maiores, as taxas de sucesso ainda sao consideraveis.
A November statement signed by all 27 Kenyan bishops pledged, "We shall not waver in calling upon all Kenyans to avoid the tetanus vaccination campaign laced with Beta-hCG, because we are convinced that it is indeed a disguised population control programme" run by who and UNICEF.
In the study, twelve tumour markers including AFP, CEA, NSE, CA125, CA15-3, CA242, CA19-9, PSA, f-PSA, FER, beta-HCG and HGH were measured by the protein biochip detection in serum in 235 pancreatic cancer patients, 230 benign pancreatic disease patients and 240 healthy people.

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