Chorionic Gonadotropin

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Related to Beta-HCG: BHCG

chorionic gonadotropin

[‚kȯr·ē′än·ik gō‚nad·ə′trō·pən]

Chorionic Gonadotropin


a hormone produced by the villi of the chorion and the placenta in some of the higher apes and in man. It is a complex protein (glycoprotein) containing the carbohydrates galactose (10.7 percent) and hexosamine (5.2 percent) and having a molecular weight of approximately 100,000. Chorionic gonadotropin has a stimulating effect on the corpus luteum, causing it to grow in size, increasing its secretory activity and prolonging its life; it converts the corpus luteum into the corpus luteum of pregnancy, which continues to secrete the hormone progesterone until the placenta is fully formed.

Chorionic gonadotropin, while similar in effect to the luteinizing hormone of the pituitary, differs from it in certain respects: it does not restore gonads atrophied after removal of the pituitary, it has no effect on avian gonads, and it causes only a slight enlargement of the ovaries in immature rodents.

References in periodicals archive ?
The remaining 1,083 women--all hemodynamically stable with beta-hCG levels below 10,000 mlU/mL, no fetal heart activity, and an intervention nearby--were assigned to the watchful waiting protocol.
Stability of intact chorionic gonadotropin (hCG) in serum, liquid whole blood, and dried whole-blood filter-paper spots: impact on screening for Down syndrome by measurement of free beta-hCG subunit.
Trophoblastic tissue secretes beta-hCG and the differential diagnosis for an elevated serum HCG concentration includes intra-uterine and extra-uterine pregnancy, gestational trophoblastic neoplasia, and ovarian germ cell tumors.
In natural, with start the first week of conception and embryo's nesting in womb's wall, the amount of beta-HCG is increase enough, it can measure in serum.
Highlight all the amino acids in 1HRP_B to turn beta-HCG yellow.
A clinical pregnancy was defined as the presence of appropriately rising beta-hCG levels and the presence of a gestational sac demonstrated by ultrasound 6 to 7 weeks after oocyte retrieval.
On the other hand, beta-hCG is present in the blood in high concentration in more than 90 percent of patients with trophoblastic malignancies.
Concerns that the antibody response to beta-hCG may have the potential to cross-react with and interrupt other hormones produced in the pituitary gland have slowed the progress of anti-hCG clinical research.
These include, for women of childbearing age, a Beta-HCG test for pregnancy.
In some of Talwar's work, beta-hCG is linked to tetanus toxoid in order to increase its overall immunity-stimulating potency while also producing immunity to tetanus.
If an ultrasound doesn't show the location of the pregnancy, obtain serial quantitative beta-HCG levels to determine whether the pregnancy is normal or abnormal, she advised.

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