lactam

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Related to Beta-lactam antibiotics: beta-lactamase, Aminoglycosides

lactam

[′lak‚tam]

(organic chemistry)

An internal (cyclic) amide formed by heating gamma (γ) and delta (δ) amino acids; thus γ-aminobutyric acid readily forms γ-butyrolactam (pyrrolidone); many lactams have physiological activity.

References in periodicals archive ?

Kounis syndrome following beta-lactam antibiotic use: review of literature.

ST-elevation Myocardial Infarction After Antibiotic Use: A Case Report of Allergy-Associated Acute Coronary Disease

sup][18] conducted a randomized controlled trial in 25 ICUs to evaluate the efficacy of continuous versus intermittent infusion of beta-lactam antibiotics in patients with severe sepsis and found no difference between treatment groups in clinical cure rates (52.

Pharmacokinetic and Pharmacodynamic Efficacies of Continuous versus Intermittent Administration of Meropenem in Patients with Severe Sepsis and Septic Shock: A Prospective Randomized Pilot Study

The authors say their study findings in mice raise the possibility that prescribing beta-lactam antibiotics to treat infections in humans may worsen the infection, should the source prove to be MRSA.

In the news: antibiotic resistance

coli because of high rate of beta-lactam antibiotics consumption in our hospitals and also a wrong culture of self- consumption of antibiotics.

Characterization of TEM-, SHV-, CTX- and AmpC-type [beta]-lactamases from cephalosporin resistant Escherichia coli isolates from Northwest of Iran

These bacteria are resistant to beta-lactam antibiotics, such as methicillin, amoxicillin, penicillin, and oxacillin.

EpiCast Report: Methicillin-Resistant Staphylococcus Aureus (MRSA) - Epidemiology Forecast to 2024

The best evidence right now is that for simple cellulitis (no purulence, abscess, or exudate), treatment with a beta-lactam antibiotic is the best option.

Myth of the month: MRSA coverage in cellulitis treatment

The MaxSignal Beta-Lactam ELISA Test Kit was developed to ease these concerns and assure that food is free of beta-lactam antibiotic residues.

Bioo Scientific Enables the Sensitive Detection of a Broad Range of Beta-Lactam Antibiotics in Food

Metallo-beta-lactamases are able to hydrolyze virtually all beta-lactam antibiotics including carbapenems.

Imipenem Resistant Pseudomonas aeruginosa: The fall of the final quarterback

Analysis of twelve beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection.

Antibiotic administration in the critically ill in need of intensive care!

Irreversible effects of serum proteins on beta-lactam antibiotics.

Increased serum protein in an elderly debilitated woman

Beta-lactamase inhibitors restore or potentiate the activity of beta-lactam antibiotics.

Roche, Meiji and Fedora join forces to tackle increasing bacterial resistance to antibiotics

and Enterome Bioscience SA have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients.