canaliculus

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Related to Bile canaliculi: canaliculus, Canal of Hering, Space of Disse

canaliculus

[‚kan·əl′ik·yə·ləs]
(histology)
One of the minute channels in bone radiating from a Haversian canal and connecting lacunae with each other and with the canal.
A passage between the cells of the cell cords in the liver.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

canaliculus

A small channel or groove, as a fluting carved on the face of a triglyph.
McGraw-Hill Dictionary of Architecture and Construction. Copyright © 2003 by McGraw-Hill Companies, Inc.
References in periodicals archive ?
Transmission electron micrograph showing DZ mouse fetal liver demonstrating the abnormal appearance of hepatocytes (H) with a large vacuole (V), erythroblasts (E) and bile canaliculi (B).
Bile produced by hepatocytes drains first into bile canaliculi, which thus represent the smallest pathway of bile flow, but these are not readily visible on an H&E stain.
The resulting failure of bile salts from hepatocytes into bile canaliculi leads to bile salt accumulation in hepatocytes, causing severe hepatocellular damage, and impaired bile flow because of the lack of bile salt secretion in bile.
Immunohistochemical stain for CD10 (original magnification X200) shows a delicate framework of bile canaliculi, which appear as linear and branching structures, creating the so-called canalicular pattern of staining.
Although there are no many findings on the principles responsible for the choleretic action, it has been suggested that polyphenol constituents of the extract may be responsible of the higher secretion of cholephilic compounds into the bile canaliculi (Gebhardt and Ueberham, 1998).
[12], we confirmed that Gd-BOPTA is transported into bile canaliculi through the multiple resistance-associated protein 2 (Mrp2) [11].
Thus, two periods are distinguished: (1) the Gd-BOPTA perfusion period that evidences how the contrast accumulates in the liver compartments, and (2) the Gd-BOPTA rinse period that investigates how the contrast leaves hepatocytes into bile canaliculi and back into sinusoids.
A polyclonal antibody directed against carcinoembryonic antigen (Quartett, Berlin, Germany) (which cross-reacts with biliary glycoprotein 1) stained bile canaliculi formed by hepatocytes, the surface of the biliary epithelium of portal tracts and BDH, as well as the cytoplasm and membranes of scattered tumor cells.