Biocatalysis


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Related to Biocatalysis: biocatalyst, biotransformation

Biocatalysis

 

the acceleration by enzymes of chemical reactions in living organisms. Biocatalysis is a process that is highly efficient and specific, and—unlike chemical catalysis—it takes place under “mild” conditions—that is, those that are natural to the living organism (temperature, pressure, reaction of the environment, and so on).

References in periodicals archive ?
Enzymes from Higher Eukaryotes for Industrial Biocatalysis. Food Technol Biotechnol.
The key difference between biocatalysis today compared with 10 years ago is the availability of all the supporting technologies, such as bioinformatics, enzyme evolution and high-throughput screening, which make a real difference in enzyme development.
Biocatalysis is Almac's first choice for any scale-up of chiral chemistry due to the cost, efficiency, robustness and 'green' benefits that result.
Note that in the case of fermentation and biocatalysis, already commercially viable, more incremental technology developments are likely to happen, simply building on existing fundamental knowledge bases to increase market share.
Robert Holt, director of Biocatalysis, said the alternative had been to take a free-standing unit on a science park, but which would have been nowhere near as attractive as The Wilton Centre.
Robert Holt, director of Biocatalysis, said: "Depending on business developments, we hope to expand our permanent team over the next few years which may require expansion into additional laboratory space.
There are several advantages that apply to biocatalysis in organic media; higher solubility of hydrophobic species, reduced microbial contamination, and reduced water activity which alters the hydrolytic equilibrium [1].
Professor Nick Turner, director of the Centre of Excellence in Biocatalysis, Biolransformations and Biocatalytic Manufacture, said: "White biotechnology has traditionally been the preserve of the pharmaceutical and fine chemical industries, but is poised to expand dramatically."
He set up the pounds 20m Centre of Excellence for Biocatalysis, Biotransformations and Biocatalytic Manufacture at Manchester University, having been head of Chemical Research at GlaxoSmithKline.
Professor Richard Gross, director of Polytechnic University's National Science Foundation (NSF) Center for Biocatalysis and Bioprocessing of Macromolecules (CBBM), developed the new bioplastic using vegetable oils.
In addition, AMRI may provide follow-up medicinal chemistry hit-to-lead optimization, biocatalysis or chemical synthesis support on compounds of interest to Bristol-Myers Squibb.