bipolar disorder

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bipolar disorder,

formerly

manic-depressive disorder

or

manic-depression,

severe mental disorder involving manic episodes that are usually accompanied by episodes of depressiondepression,
in psychiatry, a symptom of mood disorder characterized by intense feelings of loss, sadness, hopelessness, failure, and rejection. The two major types of mood disorder are unipolar disorder, also called major depression, and bipolar disorder, whose sufferers are
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. The term "manic-depression" was introduced by the German psychiatrist Emil KraepelinKraepelin, Emil
, 1856–1926, German psychiatrist, educated at Würzburg (M.D., 1878). He also studied under Wilhelm Wundt in Leipzig, and was appointed professor of psychiatry at the Univ.
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 in 1896. The manic phase of the disorder is characterized by an abnormally elevated or irritable mood, grandiosity, sleeplessness, extravagance, and a tendency toward irrational judgment. During the depressed phase, the person tends to appear lethargic and withdrawn, shows a lack of concentration, and expresses feelings of worthlessness, self-blame, and guilt. This dual character of the disorder has given it the name bipolar disorder, in contrast to the unipolar depression symptomatic of the majority of mood disorders. The symptoms range in intensity and pattern and may not be recognized at first. Individuals suffering from bipolar disorder may have long periods in their lives without episodes of mania or depression, but manic-depressives have the highest suicide rate of any group with a psychological disorder.

Incidence

Estimates suggest that about 2 million Americans suffer from bipolar disorders. Symptoms usually appear in adolescence or early adulthood and continue throughout life. The disorder occurs in males and females equally and is found more frequently in close relatives of people already known to have it.. It has had notable incidence among creative individuals, affecting such artists as Hector Berlioz, Gustav Mahler, Ernest Hemingway, and Virginia Woolf.

Treatment

Therapy includes lithiumlithium
[Gr.,=stone], metallic chemical element; symbol Li; at. no. 3; interval in which at. wt. ranges 6.938–6.997; m.p. about 180.54°C;; b.p. about 1,342°C;; sp. gr. .534 at 20°C;; valence +1. Lithium is a soft, silver-white metal.
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 (to control mania and stabilize mood swings), anticonvulsant drugs such as valproate and carbamazepine, and antidepressantsantidepressant,
any of a wide range of drugs used to treat psychic depression. They are given to elevate mood, counter suicidal thoughts, and increase the effectiveness of psychotherapy.
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. Electroconvulsive therapyelectroconvulsive therapy
in psychiatry, treatment of mood disorders by means of electricity; the broader term "shock therapy" also includes the use of chemical agents. The therapeutic possibilities of these treatments were discovered in the 1930s by Manfred Sakel, a Polish
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 has been useful in cases where other treatments have had little success. Psychotherapy can provide support to the patient and the family.

Bibliography

See F. K. Goodwin and K. R. Jamison, Manic-Depressive Illness (1990); D. Healy, Mania: A Short History of Bipolar Disorder (2011); publications of the National Institute of Mental Health.

The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/

bipolar disorder

[bī′pō·lər dis′ȯrd·ər]
(psychology)
A major affective disorder in which there are episodes of both mania and depression. Also known as manic-depressive illness.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Implications for Nursing Care of Patients with Bipolar Disorders and Their Significant Others
The efficacy of LATUDA in the treatment of mania associated with bipolar disorder has not been established.
According to the information obtained from familial, twin, adoption, linkage analysis, and molecular genetic studies aimed at understanding the genetics of bipolar disorder it has been concluded that the heredity of the disorder does not comply with the classical Mendel laws and rules (autosomal dominant, autosomal recessive, or gender-related heredity), and that there may be many gene loci and many types of heredity issues related to the disorder (4,5,9,10).
Bipolar-OCD comorbidity was first reported in a 1995 study from Germany [2] which found that more than half of all patients with bipolar disorder had experienced other mental disorders, including OCD, during the course of the bipolar disorder.
Manic-depressive illness: Bipolar disorders and recurrent depression, Second Edition.
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Data from the Course and Outcomes of Bipolar Youth study were reviewed for 413 youth aged 7-17 years (average age 13 years) with bipolar disorder; 256 study participants had comorbid anxiety.
According to the DSM-IV-TR (APA, 2000), bipolar disorders are characterized by a combination of intense and alternating mood episodes.
Bipolar disorder often goes unrecognized by primary care providers (PCPs) because patients typically present with what appears to be a major depressive episode and PCPs think it unlikely that they will see bipolar illness.
Early-onset bipolar disorder is often difficult to recognize and diagnose because distinguishing between normal behaviors and pathological behaviors in children can be challenging, and because symptoms of bipolar disorder may resemble those of, and/or co-occur with, other common childhood-onset mental disorders (Bowring & Kovacs, 1992; National Institute of Mental Health [NIMH], 2000; Papolos & Papolos, 1999).
The law requires coverage for nine specific mental-health diagnoses: schizophrenia, schizo-affective disorder, bipolar disorder major depressive disorders, panic disorder, obsessive-compulsive disorder, pervasive development disorder or autism, anorexia nervosa and bulimia nervosa.