In the present study, the onset of the blastema
formation occurred by the fourth day of regeneration in the control group.
(e) Wilm's tumor, with regressive changes, of intermediate risk with only small areas of blastema
A wandering ureteral bud may cross the midline to the contralateral side and diffuse with the contralateral metanephric blastema
, rather than the same side blastema
, resulting in the formation of a crossed ectopic kidney.
(51) From the seventeenth to nineteenth centuries, the lymph and blastema
theories dominated the oncology landscape, contending that cancer was formed by the abnormal movement of fluid throughout the body and by small blastemas
between pockets of tissue.
MRKH syndrome has been attributed to an initial affection of the intermediate mesoderm, consequently leading to an alteration of the blastema
of the cervicothoracic somites and pronephric ducts (4,12).
Salamanders, axolotls, and zebrafish respond to heart injury inducing a blastema
tissue, as part of an epimorphic regeneration .
cells then accumulate underneath the healed epidermis, which forms a thickened structure at its apex, called the apical epithelial cap (AEC) [21, 22].
The inadequate stimulation of metanephrogenic blastema
by the ureteric bud results in renal maldevelopment.
A German pathologist Johannes Muller first time demonstrated that cancer cells were originated from a bud called Blastema
instead of normal cells (Kardinal and Yarbro, 1979).
Unlike urodele limb regeneration, antler regeneration does not involve cell de-differentiation and the formation of a blastema
from the de-differentiated cells; rather, antler regeneration appears to a stem-cell-based process that requires the periodic activation of periosteal stem cells of the distal pedicle, which are presumably derived from the neural-crest (Kierdorf et al., 2007).
Radial water canals and ambulacral plates arise from the blastema
. Consequently, growth occurs from the proximal to the distal region.
It's thought to come from very specialised cells in the embryo known as metanephric blastema
. These cells are involved in the development of the child's kidneys while they're in the womb.