Ischemia

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ischemia

[i′skē·mē·ə]
(medicine)
Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.

Ischemia

 

a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.

N. R. PALEEV

References in periodicals archive ?
These criteria were compiled from our own clinical experience and have not been restricted to proof of bowel ischemia by means of CT or endoscopy since clinical suspicion often raises due to unspecific signs like delayed bowel function, distension of the abdomen, or hyperlactatemia.
Excessive release of LPS secondary to bowel ischemia and loss of barrier effect can overwhelm the portal circulation and the Kupffer cells' ability to neutralize them, resulting in entry to the general circulation where they cause significant adverse symptoms.
Patient Age Gender Peritonitis cause Mortality (year) F.A 22 Male Small and large bowel No perforation D.S 84 Female Large bowel ischemia Yes F.M 71 Male Large bowel ischemia Yes S.L 93 Female Small bowel ischemia Yes R.A 92 Female Large bowel ischemia Yes and obstruction
Mesenteric injury can lead to bowel ischemia with subsequent stenosis.
In this case classical clinical signs of small bowel ischemia such as fever, tachycardia, and peritonitis were absent; investigations were most compatible with a diagnosis of cholecystitis.
Long-term complications that can arise in patients after gastric bypass include internal hernia, small bowel ischemia, acute mesenteric venous thrombosis, and midgut volvulus.
Furthermore, nine of the patients in the probiotics group developed bowel ischemia (eight with fatal outcomes), compared with none in the placebo group.
A high index of suspicion for bowel ischemia following laparoscopic surgery should occur when, postoperatively, a patient experiences inordinately severe abdominal pain associated with tachypnea, tachycardia, and alterations in the WBC count.
SLE-related small vessel inflammation can cause bowel ischemia, particularly in AAS patients.
Of 14 patients who had an objective evaluation for bowel ischemia, 1 had minor ischemia.