1314 in two different studies described very good treatment results without recurrence after cryotherapy in patients with Bowen disease
conventionally carries with it the implication of having a strong tendency to recur after local treatment but with only a small percentage progressing to invasive squamous cell carcinoma.
AMSTERDAM -- Topical photodynamic therapy has advanced far enough that it ranks alongside other first-line therapies for actinic keratoses, Bowen disease
, superficial basal cell carcinoma, and thin nodular basal cell carcinoma, according to evidence-based guidelines issued by the International Society for Photodynamic Therapy in Dermatology.
and risk of subsequent malignant neoplasms: a population-based cohort study of 1147 patients.
AVARIOUS skin problems can cause this appearance but in your age group, and in view of the long history and steady growth of the patch, it is possible you have Bowen Disease
3,4,10 Bowen disease
and squamous cell carcinoma may develop under arsenical keratosis.