Bowman's Capsule

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Bowman's capsule

[¦bō·mənz ′kap·səl]
A two-layered membranous sac surrounding the glomerulus and constituting the closed end of a nephron in the kidneys of all higher vertebrates.

Bowman’s Capsule


(named after the 19th-century English physician W. Bowman), a cuplike cul-de-sac of the uriniferous tubule of the kidneys of vertebrate animals and humans. Bowman’s capsule surrounds the glomerulus and together they form the malpighian body. The wall of Bowman’s capsule consists of an inner and outer layer, between which is a gap—the cavity of Bowman’s capsule—lined with a flat epithelium. The inner layer adheres to the glomerulus, and the outer layer becomes the beginning of the uriniferous tubule. In Bowman’s capsule, so-called primary urine is formed.

References in periodicals archive ?
The Bowman's capsule BM shows a significant increase of 8% in average thickness under diabetic conditions but only of 3% in EGb-protected animals without significant difference to the controls (Table 2).
EGb 761 showed some beneficial effects in STZ diabetic rat kidneys: glomerular hypertrophy, dilation of the capsular space, thickening of Bowman's capsule BM, ultrastructural lesions on capillaries and podocytes were reduced, increase in collagen fibers of type I, III, and VI in the tubular interstitium was diminished, increased SOD activity was equalized.
Bowman's capsule is made up of two cell layers: the visceral layer that forms the epithelial layer (podocytes) of the filtration barrier and the parietal cell layer that forms the outer layer of the capsule.
In respect to the Bowman's capsule, the mean values were 101,836.
Fluid that is filtered through the glomerulus and into Bowman's capsule is labeled glomerular filtrate.