busulfan

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busulfan

[‚byü′səl·fən]
(pharmacology)
CH3SO2O(CH2)4OSO2CH3 Crystals with a melting point of 114-118°C; soluble in acetone at 25°C; used as an antineoplastic drug.
References in periodicals archive ?
The company stated that the Myleran (busulfan) Injection, 60 mg/10 ml (6 mg/ml) single-dose vial is the generic version of Otsuka Pharmaceutical's Busulfex Injection.
In the hospital setting, ESP's IV Busulfex is marketed as a preconditioning chemotherapeutic agent in bone-marrow transplant, and is a natural fit in view of our right to potentially reacquire the rights to Zenapax in the transplant indication by 2007."
Kirin has strong presence in hematology field through its product pipeline including CliniMACS, Busulfex and second-generation of G-CSF in Japan.
General and administrative costs will decrease slightly following the sale of Busulfex and related staff changes.
ESP Pharma, Inc., Edison, NJ, announced it has acquired from Orphan Medical, Inc., Minnetonka, MN, worldwide rights to Busulfex Injection, an intravenous formulation of the alkylating agent busulfan, a drug often used in bone marrow transplantation.
This investment in oncology is also illustrated by major efforts in R&D partnerships, such as the licensing agreement with Orphan Medical for Busulfex in 1999, and research agreements signed last year with Celera Genomics and other biotechnology companies.
Four patients with different kinds of malignancies [high-grade non-Hodgkin lymphoma (n = 2), Hodgkin disease (n = 1), and plasmocytoma (n = 1)] were treated with Busulfex [TM] [6 g/L solution of busulfan dissolved in N,N-dimethylacetamide-polyethylene glycol (33:67 by volume); Orphan Medical] in conditioning regimes for HSCT.