The diagnosis of tetanus is made based on clinical findings because the bacterium C. tetani
is difficult to grow from wounds.
is a ubiqutous organism which get entry into host from cuts and bruish on skin.
In a recent series of 12 patients (2), only 1 case of posttraumatic osteoarticular infection was caused by C. tetani (fracture of the distal humerus with polymicrobial infection).
To the best of our knowledge, the only case of C. tetani infection with a toxigenic strain but without tetanus or osteitis was a wound infection that quickly improved after administration of antitetanus vaccine, prophylactic immunoglobulins, flucloxacillin, and metronidazole (3).
A bone biopsy sample revealed Enterococcus faecalis, Enterobacter cloacae, and C. tetani. Identification of C.
But if C. tetani penetrates into the sealed and oxygen-free regions of an animal's system, it can thrive happily and will start to replicate wildly within a matter of hours.
Why does C. tetani choose this uniquely insidious way of stirring up trouble?
El genero Clostridium esta representado por bacilos anaerobios productores de esporas, habitantes normales del suelo e incluye los dos agentes productores de las neurotoxinas naturales mas poderosas: C. tetani y C.
Para la identificacion de las cepas toxigenicas de C. tetani se inocula por triplicado 0.1 ml de un sobrenadante libre de celulas del cultivo sospechoso en ratones jovenes (con un peso corporal menor de 20 g).
Penicillin is the drug of first choice and was used locally and parenterally for a week to kill any vegetative C. tetani
organism present in the wound.
We conclude the outbreak resulted from severe environmental C. tetani contamination.
C. tetani was isolated from this lesion, and the tetanus toxin gene was detected by PCR.