chemokine

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chemokine

[′kē·mə‚kīn]
(cell and molecular biology)
A small (7-14 kilodaltons of soluble protein) chemoattractant cytokine produced by cells and tissues at the beginning of an immune system response to infection, allergen, injury, and so forth that controls the nature and magnitude of immune cell infiltration and inflammation at the affected site.
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2013) Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses.
CXCR3 and CCL1 genes selected for the study were amplified from cDNA of macrophages (Fig.
Then the cytokines TNF-a IL6 (M1 markers) and IL10 CCL1 (M2 mar-kers) secreted by BMDM were detected using ELISA.
Immune response genes selected for the study (TLR2, NFKB1, IL2, IL16, TNF, IFNG, CXCR3, CCL1, CD81, CD84, RPS6KB2, STK17B, PRKCB1, MCL1, EEF1G, NFATC4, EEF1 and IER5) were amplified from cDNA of PBMCs (Fig.