cytotoxic T cell

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Related to CD8 T cells: CD4 T cells, Cytotoxic T lymphocytes

cytotoxic T cell

[¦sīd·ə‚täk·sik ′tē ‚sel]
(immunology)
A type of T cell which protects against pathogens that invade host cell cytoplasm, where they cannot be bound by antibodies, by recognizing and killing the host cell before the pathogens can proliferate and escape.
References in periodicals archive ?
To answer this question, CD8 T cells were purified from 2C TCR transgenic mice and stimulated with UVADEX-treated or nontreated Drosophila APC Fly/[L.sup.d]/B7.1/ICAM.
A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes.
"We already know how to stimulate the immune system to make CD8 T cells by vaccination.
Antigen-independent memory CD8 T cells do not develop during chronic viral infection.
Activation of memory CD8 T cells upregulates CD38 expression, which makes it a good marker of cellular activation in this subset.
The subjects taking the combination tonic also showed increased CD69 activation, expressed primarily on CD8 T cells, and to a lesser extent on CD4 T cells and NK cells.
Defective CD8 T cell memory following acute infection without CD4 T cell help.
Aurelian notes that both dl5-29 and Delta PK hike production of a CD8 T cell protein called interferon gamma.
But don't be fooled: the virus is under tremendous selective pressure from the immune system and is trying (and largely succeeding) to stay at least a step ahead of neutralizing antibodies and CD8 T cells (and probably other aspects of the immune response).
These results suggest that patients with the highest complement of CD8 T cells will likely experience the most significant therapeutic response to rhIL-12, Dr.