This study finds that a single CD8 count
has important prognostic significance in patients with advanced HIV infection and suggests that potential therapies to CD8 counts
might be beneficial to patients with advanced HIV infection.
Statistical analysis that considered antiretroviral exposure, CD4 and CD8 counts
, and a melange of classic risk factors determined that a current viral load above 50 copies/mL (versus below) independently raised the odds of a new MI 51% (adjusted odds ratio 1.51, 95% CI 1.09 to 2.10).
A double-blind placebo-controlled trial of multivitamins plus selenium in 400 HIV-infected nonpregnant Kenyan women found that supplementation significantly boosted CD4 and CD8 counts
but--defying expectation--significantly increased vaginal shedding of HIV.
There was also a significant negative correlation for MIP1[beta] with lymphocyte per cent, lymphocyte count, CD4 per cent, CD4 count and CD8 count
. There was a negative correlation between RANTES values and CD 8 per cent (Table III).
Table 1: Percentages of CD4 and CD8 and absolute CD4 and CD8 counts
before and after immunization in the controller and noncontroller groups and total population.
Greenberg et al., "Decreased CD4 and increased CD8 counts
with T cell activation is associated with chronic helminth infection," Clinical and Experimental Immunology, vol.
Whole blood, serum or plasma were collected from all subjects and eight markers were measured: Hemoglobin and platelets measured by cell counter (sysmex, KX21- Japan); Homocysteine measured by auto-analyzer (Alcion-300, Abott-USA), Turbidometric method; Anticardiolipin and Antiphospholipid antibodies (IgG, IgM) measured by ELISA method and lymphocyte CD4, CD8 counts
were done by a single platform flow cytometric method.
A pilot study on observations on CD4 & CD8 counts
in healthy HIV seronegative individuals.
Neither did total and naive CD4 and CD8 counts
. Levels of Haemophilus influenzae type B protective antibodies in response to vaccination were comparable in the two groups.
"The endless stream of numbers--CD4 and CD8 counts
, ratios, white and red blood cell counts, liver enzymes--is enough to leave anyone frustrated and confused.
Blood investigations including complete haemogram, biochemistry (including--blood sugar, renal function tests, liver function tests) and CD4/ CD8 counts
were carried out.