cyclin-dependent kinase

(redirected from CDK4 gene)
Also found in: Medical.

cyclin-dependent kinase

[¦sī·klin di¦pen·dənt ′kī‚nās]
(cell and molecular biology)
A family of kinases that, once activated by cyclin, regulate the cell cycle by adding phosphate groups to a variety of protein substrates that control processes in the cycle. Abbreviated Cdk.
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References in periodicals archive ?
For example, we know a faulty CDKN2A and CDK4 gene indicates that you're at greater risk for melanoma.
Personalize your cancer treatment
Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclindependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression.
Comparison of antimalarial activity of Artemisia turanica extract with current drugs in vivo
Burrows does not recommend testing for the CDKN2A and CDK4 gene mutations in most patients.
Multiple melanomas a real phenomenon

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