DNA microarray

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Related to CDNA microarray: Oligonucleotide microarray

DNA microarray

[¦dē¦en¦ā ′mī·krō·ə‚rā]
(cell and molecular biology)
A microscopic spot containing identical single-stranded polymeric molecules of deoxyribonucleotides (DNAs), usually oligonucleotides or complementary DNAs, attached to a solid support (such as a membrane, a polymer, or glass) used to simultaneously analyze the expression levels of the corresponding genes.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Yang, "Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation," Nucleic Acids Research, vol.
Gene expression profiling of Spodoptera frugiperda hemocytes and fat body using cDNA microarray reveals polydnavirus-associated variations in lepidopteran host genes transcript levels.
Yan, "HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments," BMC Bioinformatics, vol.
Use of a cDNA microarray to analyse gene expression patterns in human cancer.
Speed, "Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments," Statistica Sinica, vol.
To better understand the mechanism for the apigenin action, cDNA microarray hybridization, quantitative reverse transcription-polymerase chain reaction (qPCR), and Western blot analysis were performed to identify potential genes involved in the apigenin function.
Respondents using technology (%) Array type In 2005 In 2006 In 2007 One-channel oligo microarray 38.2 40.2 45.1 Two-channel oligo microarray 22.5 22.5 21.6 cDNA microarray 19.6 17.6 16.7 Other high-density transcriptiomics 6.9 6.9 11.8 Organizational capacity and resource allocation.
High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma.
Topics include molecular analysis of genetic instability caused by chronic inflammation, inflammation-related aberrant patterns of DNA methylation, cDNA microarray analysis of inflammatory breast cancer signatures, induced nitric oxide synthase as a major player in the oncogenic transformation of inflame tissue, development of a cell-based assay to quantify the inflammatory potential of test substances and screen compound libraries for anti-cancer drug candidates in high-throughput format, quantitative measurement of cytokine expression in synoviocytes derived from rheumatoid arthritis patients, investigating macrophage and malignant cell interactions in vitro, and the molecular basis of histone deacetylase inhibitors as new drugs for the treatment of inflammatory diseases and cancer.
A number of previous researches have utilized cDNA microarray analyses to reveal differential expression of genes in various pig tissues (Kim et al., 2005; Guo et al., 2008).
In cDNA microarray images, the assumption of circular spot shape is not justified due to artifacts caused by the printing process and the hybridization technique.