Effects of Human Lung Mast Cell Products on ASM Cell CXCL10
. Asthmatic and non-asthmatic ASM cells responded in a similar way to the products released by human lung MC, but the effects of the 2 h and 24 h MC SN on ASM cell CXCL10
Concentrations of CXCL8, CXCL10
, MMP-2, sVEGFR1, sVEGFR2, and HGF in supernatants were determined in duplicates using Quantikine enzyme-linked immunosorbent assays (ELISA) (R&D Systems, Minneapolis, MN, USA).
Sera were separated from blood and analysed for 14 different molecules: interleukin (IL)-2, IL-6, IL-10, IL-12p70, interferon (IFN)-[gamma] macrophage migration inhibitory factor (MIF), tumor necrosis factor (TNF)-[alpha], TNF-related apoptosis inducing ligand (TRAIL), sFas and Fas ligand (sFasL), and chemokines CXCL10
, CCL2, CCL3, and CCL4 as previously described .
Davis, "a-Synuclein potentiates interleukin-1[beta]-induced CXCL10
expression in human A172 astrocytoma cells," Neuroscience Letters, vol.
Increased expression of the chemokine receptor CXCR3 and its ligands CXCL10
in peripheral airways of smokers with chronic obstructive pulmonary disease.
in response to a microenvironment enriched with Th1 cytokines (IFN-[gamma], GM-CSF, IL-12, ROI, RNI, iNOS, and CXCL10
The Penn-led team showed that a specific chemokine, CXCL10
, and its receptor were abundantly produced in the brains of T.
DNA microarray analysis of several genes known to be strongly regulated during gastrointestinal inflammation, combined with quantitative real-time PCR (qRT-PCR) revealed that the apple juice extract AE04 (100-200 microg/mL) significantly inhibited the expression of NF-kappaB regulated proinflammatory genes (TNF-alpha, IL-1beta, CXCL9, CXCL10
), inflammatory relevant enzymes (COX-2, CYP3A4), and transcription factors (STAT1, IRF1) in LPS/IFN-gamma stimulated MonoMac6 cells without significant effects on the expression of house-keeping genes.
9:15 CXCL4 AND CXCL10
PREDICT RISK OF FATAL CEREBRAL MALARIA,
McNamara ve ark.'lari (45), CXCL10
eksikliginde apopitotik notrofillerin ortamdan kaldirilamamasi sonucunda iceriklerinin dokulara yayilarak doku hasarini arttiracaklari ni gostermislerdir.
Expression analysis of the T-cell-targeting chemokines CXCL9 and CXCL10
in mice and humans with endothelial infections caused by rickettsiae of the spotted fever group.