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Cerebrospinal fluid CXCL13 in multiple sclerosis: A suggestive prognostic marker for the disease course.
Additionally, the chemokine CXCL13, ubiquitin UBD, and somatomedin SBSPON play roles in inflammatory responses, and their expressions were elevated in NAFLD rats (Figure 2).
The chemokines CCL2, CCL3, CCL5, CXCL10, CXCL12, CXCL13, and CX3CL1 are expressed in the nephritic kidney of lupus-prone mice and SLE patients and increase inflammatory cell infiltration into the kidney .
Protein-protein interaction studies revealed a close interaction among CCL27 and CXCL13 but not CCL15.
This process enhances the synthesis of CXC chemokine ligand 13 (CXCL13), which is a chemoattractant of B cell follicles in lymphoid tissues, and increases the expression of B cell-activating factor (BAFF), which is an important factor for B cell survival and TGF-[beta] .
Wood et al., "Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjogren's syndrome," Arthritis Research & Therapy, vol.
CXCL13 as a cerebrospinal fluid marker for neurosyphilis in HIV-infected patients with syphilis.
(8,16) Although it may be reasonable to regard primary cutaneous acral [CD8.sup.+] T-cell lymphoma as a [CD8.sup.+] analogue to [CD4.sup.+] primary cutaneous small/medium-sized pleomorphic cutaneous T-cell lymphoma, studies have shown that the neoplastic [CD4.sup.+] T cells in the latter coexpress programmed death receptor-1 (PD-1), B-cell lymphoma 6 (BCL6), chemokine ligand 13 (CXCL13), and inducible T-cell costimulator (CD278), indicating a follicular helper T-cell phenotype.
(2,17) In the peripheral lymph nodes, LFA-1 on T cells is activated when HEV-associated chemokines including CCL21/ CCL19 and CXCL12 interact with their specific receptors on T cells, CCR7 and CXCR4, respectively, whereas LFA-1 on B cells is activated by interactions with CXCL13 via CXCR5.
Interleukin-17-dependent CXCL13 mediates mucosal vaccine-induced immunity against tuberculosis.
IL1beta and TNFalpha differently modulate CXCL13 chemokine in stromal cells and osteoblasts isolated from osteoarthritis patients: evidence of changes associated to cell maturation.
Shibuya et al., "A distinct human CD4+ T cell subset that secretes CXCL13 in rheumatoid synovium," Arthritis and Rheumatism, vol.
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