hlp

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hlp

(filename extension)
A Microsoft Windows filename extension for hypertext WinHelp files. These are in a proprietary format, and are compiled from source files written in a dialect of RTF.

See also gid.

Usenet newsgroup: news:comp.os.ms-windows.programmer.winhelp.
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References in periodicals archive ?
The maximum recommended dosage in patients taking strong CYP3A4 inhibitors is 20 mg once daily.
The drug is available in 20-mg or 40-mg doses, but the maximum recommended dosage in patients taking CYP3A4 inhibitors and those with moderate hepatic impairment is 20 mg once daily.
The most studied flavonoid-drug interactions are the interactions with the CYP3A4. There are various studies about that, flavonoids can modulate drug metabolism; by changing the expression and/or activity of cytochrome P450 enzymes.
Several studies have suggested that the amount of fentanyl metabolites correlates with CYP3A4 expression and catalytic activity.[7]
Vladimir Maletic, MD, MS, explains: "LATUDA is metabolized in the liver, primarily by CYP3A4 [cytochrome P450 3A4]...
The method, which we call CypCel is based on a drug biomarker simvastatin, a cholesterol reducing medication, that has the unusual property of being highly metabolised in the small intestine by the enzyme CYP3A4, which is expressed on the villi.
They are known to cause DDIs, mainly via inhibition of CYP3A4 (32).
The 3D liver tissue can be maintained in culture for more than a month, with stable albumin, transthyretin, alpha-1 antitrypsin, and metabolic P450 (CYP3A4, CYP1A2) enzyme protein expression levels that are typically found in mature human liver tissue.
(4,5) The CYP3A subfamily consists of 4 members: CYP3A4, CYP3A5, CYP3A7, and CYP3A43 (5) The CYP3A4 enzyme is the most abundant CYP isoform in the liver and intestine, representing 60% and 70% of the total P450 amount, respectively.
Furthermore, research suggests CYP3A4 induction by herbal medicines containing SJW is directly related to hyperforin dose ingested.
- Use with caution in patients receiving concomitant medications primarily metabolized by CYP3A4. The plasma concentrations of CYP3A4 substrates can increase when co-administered with AKYNZEO.