Cachexia


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cachexia

[ka′kek·sē·ə]
(medicine)
Weight loss, weakness, and wasting of the body encountered in certain diseases or in terminal illnesses.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Cachexia

 

a state of profound wasting and physical debility manifested by severe emaciation, weight loss, dry and flabby skin, loss of hair, disappearance of subcutaneous fat, atrophy of muscles and viscera, and low serum protein level. Edema, hemorrhages, and sometimes mental derangement can occur with cachexia. It results from prolonged malnutrition or starvation, severe metabolic disorders, chronic arsenic, lead, mercury, or fluorine poisoning, and severe lesions of the digestive tract (atrophy of the intestinal mucosa, condition after resection of the stomach and intestines). Cachexia may occur in severe cases of tuberculosis or other chronic infections, some lesions of the endocrine glands, (hypophysis, thyroid, adrenals, pancreas), large slow-healing wounds, abscesses, and malignant tumors (especially of the esophagus and stomach).

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The researchers found that 21 per cent of patients had developed cachexia one year later, meaning they had lost at least 5 per cent of their body weight.
The researchers found that metal-ion transporter ZIP14 is a critical mediator of cancer-induced cachexia. In cachectic muscles of mice and in patients with metastatic cancer, ZIP14 is upregulated and can be induced by tumor necrosis factor (TNF)-?
Biotechnology company Creative Medical Technology Holdings Inc (OTCQB:CELZ) reported on Friday the launch of a AmnioStem universal donor stem cell programme in treating cancer associated wasting (Cachexia) under President Trump's new Right to Try law.
The problem is that these additional calories can actually worsen cancer cachexia. That's because cancer cachexia isn't caused by lack of calories, but by inflammation engendered in various ways by the presence of the cancer.
MA is an appetite stimulant used in patients with anorexia and cachexia mainly secondary to cancer and HIV/AIDS.
Profound loss of adipose tissue is the hallmark of cachexia. It is estimated that approximately 20% of deaths in cancer patients are due to cachexia [1].
Cachexia is an extremely serious syndrome manifested by anorexia, weight loss through loss of muscle mass and fatty tissue, inflammation, and increased energy consumption that occurs in many chronic diseases, of which cancer occupies a special place (80% of patients with cancers develop cachexia) [1].
Neruda was suffering from prostate cancer at the time and cachexia - cancer wasting syndrome - was listed as the official cause of his death on September 23, 1973, reports Efe news.
Thus, it is assumed that new adjuvant antiinflammatory therapeutic approaches as a complementary therapy may be helpful in preventing of malnutrition and cachexia by down regulate inflammatory signaling pathways.4
Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics".