ibuprofen

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ibuprofen

(ī`byo͞oprō'fən), nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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 and ketoprofenketoprofen
, nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation.
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, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967. Like other NSAIDs, it acts by inhibiting the body's production of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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. Available over the counter in a variety of preparations (e.g., Advil, Motrin, Nuprin), it is commonly used to treat rheumatoid arthritis, gout, and painful menstruation. Side effects include rash, alteration of platelet function and bleeding, and intestinal upset, which can lead to gastritis. Like other NSAIDS, it appears to have no potential for abuse or physical dependence. It should not be used by those who are allergic to aspirin.
References in periodicals archive ?
Under the terms of the multi-year collaboration, Piramal will help expand Cumberland's reach for Caldolor And Vaprisol by providing coverage to an additional group of hospitals where Piramal's critical care sales force has existing relationships.
In conjunction, the multi-year collaboration will provide expanded sales promotion for Caldolor And Vaprisol, increased communication to medical professionals, as well as support patient care throughout the US.
According to the terms of the agreement, Alveda Pharma will seek Canadian regulatory approval for Caldolor and, upon approval, handle ongoing regulatory requirements as well as product marketing, distribution and sales throughout Canada.
Caldolor is used primarily in hospitalized patients who are unable to receive oral therapies for pain relief and fever reduction.
According to the company, Caldolor is an intravenous formulation of ibuprofen, approved by Therapeutic Goods Administration (TGA) in Australia, as a new injectable, non-narcotic treatment for pain and reduction of fever in adults.
Following the approval, Caldolor is distributed in Australia by Seqirus, a part of the CSL Group, under license agreement with Cumberland Pharmaceuticals.
Sandor Medicaids will make upfront and milestone payments, a transfer price and sales based royalties of Caldolor to Cumberland.
We are pleased to partner with Phebra to make Caldolor available in Australia and New Zealand," said A.
According to Cumberland, Caldolor (ibuprofen) Injection is the first injectable treatment for pain and fever approved in the US; Vaprisol (conivaptan) Injection is used for the treatment of hyponatremia and Omeclamox-Pak for the treatment of H.
Speciality pharmaceutical company Cumberland Pharmaceuticals Inc (NasdaqGS:CPIX) said on Wednesday that it has received top-line results from a clinical paediatric pain study of Caldolor (ibuprofen) Injection in treating pain in tonsillectomy patients ranging from 6 to 16 years old.
Pharmaceutical company Cumberland Pharmaceuticals Inc (Nasdaq:CPIX) revealed on Tuesday the execution of an exclusive agreement for the commercialisation of Acetadote and Caldolor Injection with China's Harbin Gloria Pharmaceuticals Co Ltd (SHE:002437.
Designed to treat pain and fever in the hospital setting, Caldolor was approved by the US Food and Drug Administration (FDA) and launched by Cumberland in the United States earlier this year.