ibuprofen

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ibuprofen

(ī`byo͞oprō'fən), nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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 and ketoprofenketoprofen
, nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation.
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, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967. Like other NSAIDs, it acts by inhibiting the body's production of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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. Available over the counter in a variety of preparations (e.g., Advil, Motrin, Nuprin), it is commonly used to treat rheumatoid arthritis, gout, and painful menstruation. Side effects include rash, alteration of platelet function and bleeding, and intestinal upset, which can lead to gastritis. Like other NSAIDS, it appears to have no potential for abuse or physical dependence. It should not be used by those who are allergic to aspirin.
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References in periodicals archive ?
The Company's portfolio of FDA approved brands includes: Acetadote (acetylcysteine) Injection, for the treatment of acetaminophen poisoning; Caldolor (ibuprofen) Injection, for the treatment of pain and fever; Kristalose (lactulose) for Oral Solution, a prescription laxative, for the treatment of chronic and acute constipation; Omeclamox-Pak, (omeprazole, clarithromycin, amoxicillin) for the treatment of Helicobacter pylori (H.
Caldolor is indicated in adults and pediatric patients for the management of mild to moderate pain and management of moderate to severe pain as an adjunct to opioid analgesics, as well as the reduction of fever.
Caldolor (ibuprofen) Injection is reportedly the first injectable product approved in this country for the treatment of pain and fever in adults.
According to the terms of the agreement, Alveda Pharma will seek Canadian regulatory approval for Caldolor and, upon approval, handle ongoing regulatory requirements as well as product marketing, distribution and sales throughout Canada.
According to the company, Caldolor is an intravenous formulation of ibuprofen, approved by Therapeutic Goods Administration (TGA) in Australia, as a new injectable, non-narcotic treatment for pain and reduction of fever in adults.
"We are pleased to partner with Phebra to make Caldolor available in Australia and New Zealand," said A.J.
Under the terms of the agreement, Piramal Critical Care will co-promote two of Cumberland's branded hospital products, Caldolor and Vaprisol throughout the US.
Speciality pharmaceutical company Cumberland Pharmaceuticals Inc (NasdaqGS:CPIX) said on Wednesday that it has received top-line results from a clinical paediatric pain study of Caldolor (ibuprofen) Injection in treating pain in tonsillectomy patients ranging from 6 to 16 years old.
Pharmaceutical company Cumberland Pharmaceuticals Inc (Nasdaq:CPIX) revealed on Tuesday the execution of an exclusive agreement for the commercialisation of Acetadote and Caldolor Injection with China's Harbin Gloria Pharmaceuticals Co Ltd (SHE:002437.SZ ).
Designed to treat pain and fever in the hospital setting, Caldolor was approved by the US Food and Drug Administration (FDA) and launched by Cumberland in the United States earlier this year.
In conjunction, DB Pharm Korea Co Ltd, Cumberland Pharmaceuticals Inc's commercial partner for Caldolor (ibuprofen) Injection in South Korea, has submitted an application for regulatory approval of the pain management product in that country, marking the first such submission in Asia.