Candida


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candidiasis

candidiasis (kănˌdĭdīˈəsĭs), infection caused by fungi of the genus Candida; also called moniliasis after a former name of the genus. The most common forms of candidiasis, caused by C. albicans, are infections of the mucous membranes of the mouth (also known as thrush) and of the vagina and often the vulva (also known as yeast infection). The fungus C. albicans is a normal inhabitant of the mouth and vagina, and its growth is usually kept in check by certain bacteria that also live in these areas. When the balance of these organisms is disturbed by antibiotic treatment, by hormonal imbalances, or by a weakening of the body's resistance to disease (as occurs in AIDS), the fungus can begin to proliferate. Candidiasis of the penis (usually traceable to a female with the infection) is called balanitis. Candidal infections are most often treated topically with antifungal drugs such as clotrimazole, nystatin and miconazole, but oral or intravenous antifungal drugs are prescribed when the infection does not respond to topical treatments.

Invasive candidiasis, a more serious infection, occurs most commonly when Candida fungi invade the bloodstream. Hospital and nursing home patients, such as those with a central venous catheter, in an intensive care unit, with weakened immune system, or taking broad-spectrum antibiotics, are most likely to develop invasive candidiasis. Antifungal medications may be prescribed prophylactically to patients who are likely to develop invasive candidiasis. An invasive infection is typically treated by an echinocandin administered intravenously.

C. auris, another species that causes invasive candidiasis, typically infects the bloodstream, wounds, or the ear, and especially affects individuals with weakened immune systems. First identified in Japan in 2009, it is of concern because most forms of the fungus are drug resistant and some are multidrug resistant; additionally, infection can be difficult to identify from its primary symptoms of fever, aches, and fatigue. It has caused outbreaks in health-care facilities, where it can be difficult to eradicate.

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Candida

[′kan·də·də]
(mycology)
A genus of yeastlike, pathogenic imperfect fungi that produce very small mycelia.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

Candida

ever faithful to husband. [Br. Lit.: Candida]
Allusions—Cultural, Literary, Biblical, and Historical: A Thematic Dictionary. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Invasive candida infection can lead to shock and organ failure.
In her demurrer, Candida said that the prosecution has not presented the required quantum of evidence to prove her guilt beyond a reasonable doubt.
In 2014, the Office of the Ombudsman ordered the suspension of Candida and Pedro, along with co-accused municipal treasurer Ruben Baet for the case.
In this study, we investigated in vitro antifungal activity of green tea and quince leaf on Candida isolates obtained from blood cultures.
Among the 23 infections in these 22 patients, the most common Candida species identified were Candida glabrata, Candida albicans, and Candida parapsilosis (Table).
Candida albicans is considered as an important fungal pathogen among humans because of its varying virulence factors that leads to candidiasis like phenotypic switching, phospholipase, proteinase and hemolytic activity.
When the candida yeast spreads in the mouth and throat, it causes an infection called oral thrush, or oropharyngeal candidiasis.
Strains: Candida albicans (ATCC 14053 and 64546) and Candida krusei (ATCC 6258) strains were used as a reference and eight different clinical isolates of Candida spp were evaluated in this study.
High-risk areas for Candida infection include neonatal, paediatric and adult ICUs, both medical and surgical [4] and Candida infections can involve any anatomical structure.
Last year Candida - who has also published six historical fiction novels under the name Candida Clark - began experimenting with botanical tinctures extracted from the garden's flowers and herbs.
The genus Candida consists of a group of ubiquitous yeasts with diverse characteristics.