Candida

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candidiasis

candidiasis (kănˌdĭdīˈəsĭs), infection caused by fungi of the genus Candida; also called moniliasis after a former name of the genus. The most common forms of candidiasis, caused by C. albicans, are infections of the mucous membranes of the mouth (also known as thrush) and of the vagina and often the vulva (also known as yeast infection). The fungus C. albicans is a normal inhabitant of the mouth and vagina, and its growth is usually kept in check by certain bacteria that also live in these areas. When the balance of these organisms is disturbed by antibiotic treatment, by hormonal imbalances, or by a weakening of the body's resistance to disease (as occurs in AIDS), the fungus can begin to proliferate. Candidiasis of the penis (usually traceable to a female with the infection) is called balanitis. Candidal infections are most often treated topically with antifungal drugs such as clotrimazole, nystatin and miconazole, but oral or intravenous antifungal drugs are prescribed when the infection does not respond to topical treatments.

Invasive candidiasis, a more serious infection, occurs most commonly when Candida fungi invade the bloodstream. Hospital and nursing home patients, such as those with a central venous catheter, in an intensive care unit, with weakened immune system, or taking broad-spectrum antibiotics, are most likely to develop invasive candidiasis. Antifungal medications may be prescribed prophylactically to patients who are likely to develop invasive candidiasis. An invasive infection is typically treated by an echinocandin administered intravenously.

C. auris, another species that causes invasive candidiasis, typically infects the bloodstream, wounds, or the ear, and especially affects individuals with weakened immune systems. First identified in Japan in 2009, it is of concern because most forms of the fungus are drug resistant and some are multidrug resistant; additionally, infection can be difficult to identify from its primary symptoms of fever, aches, and fatigue. It has caused outbreaks in health-care facilities, where it can be difficult to eradicate.

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Candida

[′kan·də·də]
(mycology)
A genus of yeastlike, pathogenic imperfect fungi that produce very small mycelia.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

Candida

ever faithful to husband. [Br. Lit.: Candida]
Allusions—Cultural, Literary, Biblical, and Historical: A Thematic Dictionary. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Outbreak of candidemia caused by fluconazole resistant Candida parapsilosis strains in an intensive care unit.
Multidrug transporters and alterations in sterol biosynthesis contribute to azole antifungal resistance in Candida parapsilosis. Antimicrob Agents Chemother.
In this report, although the presence of cryptic species of Candida parapsilosis and Candida glabrata were not observed, it is important to use methodologies that are able to detect them, mainly due to the emergence of species that are difficult to manage (9,37,38).
Fernandez-Ruiz et al., "Initial use of echinocandins does not negatively influence outcome in Candida parapsilosis bloodstream infection: a propensity score analysis," Clinical Infectious Diseases, vol.
Inoculum preparation: Antifungal activity on clinical strains; Candida albicans, Candida tropicalis, Candida parapsilosis, Candida glabrata and control strains Candida parapsilosis ATCC 22019 and Issatchenkia orientalis (Candida krusei) ATCC 6258 were evaluated.
These 2 episodes occurred with a time difference of more than 5 months and were caused by Candida parapsilosis, although in one of the episodes bacterial agents were also isolated.
Candida parapsilosis es un hongo levaduriforme, ubicuo, comensal del tejido epitelial y mucosas del humano, que no habia sido considerado como un patogeno importante, hasta que se aislo de infecciones severas en pacientes inmunocomprometidos y drogadictos (1).
albicans were D1, D2, D4, D7, D18, and D20 and non-albicans species include ATCC 90030 (Candida glabrata), D9 (Candida tropicalis), D11 (Candida parapsilosis), and D46 (Candida krusei).
If we put a more broad look at geographical distribution of the pathogens, Candida glabrata isolates are more common in North America (23.5%), Candida albicans isolates are more common in Asia Pacific region (56.9%), with Candida parapsilosis (25.6%) and Candida tropicalis (17.0%) being more prominent in Latin American region15.
Candida parapsilosis endocarditis: A comparative review of the literature.
Tres comunicagoes curtas: Candida parapsilosis as vero cell culture contaminant in neospora caninum antigen production; Ausencia de bacteriofagos liticos para salmonella enteritidis em amostras de ambientes avicolas no noroeste do estado de Sao Paulo; e Importancia do exame coprologico no diagnostico da euritrematose bovina.