Capillaroscopy


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Capillaroscopy

 

an intravitam method of study involving the examination, under magnification, of capillaries of the epithelial or endothelial integuments of animals and man (skin, mucous membranes).

In man, the capillaries are examined in the skin fold of the nail bed, where they can be viewed most conveniently. A microscope or a special instrument, the capillaroscope, is used for this purpose. The use of the microscope (20–100 power magnification) after the application of a drop of clarifying oil to the skin and good oblique illumination provide good visibility. Changes are observed in the capillaries with disturbances of the peripheral blood circulation of a variety of etiologies (in vascular neuroses, the early stages of cardiac insufficiency, end arteritis obliterans). The changes observed during capillaroscopy are not strictly specific to a given pathological condition; they arise as an adaptive mechanism to any disturbance of the general blood flow. There-fore, capillaroscopy is used only as a supplementary diagnostic method in general clinical examinations.

References in periodicals archive ?
Dr.Khalid Ali Khan from UAE was the last speaker in this session whose presentation was on "Nail fold Capillaroscopy".
Updating the American college of Rheumatology preliminary classification criteria for systemic sclerosis: addition of severe nail fold capillaroscopy abnormalities markedly increases the sensitivity for limited scleroderma.
Nailfold video capillaroscopy can be used to examine the retinal damage-related capillary changes, indicating a generalized microvessel involvement in both type 1 and 2 diabetic patients [18, 21].
Advise them to ask their GP for an ANA blood test and a capillaroscopy.
Examination revealed erythematous plagues over extensor surfaces, abnormal nail fold capillaroscopy, and mild bilateral lower extremity proximal weakness.
[18] Morf et al., [19] using intravital capillaroscopy in FMS patients, found morphological abnormalities indicating capillary dilatation, indicating functional impairment in microcirculation in this patient population.
Similar results were obtained when laser Doppler flowmetry was used to assess the response of choroid vascular blood flow to hypoxia and high concentration of CO[sub]2 in patients with simple OSAS and healthy controls.[sup][14] In contrast, capillary density in forearm and perineal area, calculated by capillaroscopy, in patients with severe OSAS complicated with mild untreated hypertension, was significantly decreased compared with healthy controls.[sup][15]
Moreover, nailfold capillaroscopy is very helpful as a screening method for detecting patients with RP at high risk for the development of connective tissue disease [11-13].
Caption: Nailfold capillaroscopy images show progressively worsening damage: microhemorrhage and hemosiderin (top left), an Isolated dilated loop (top right), lower capillary density and microhemorrhage (lower right), and architectural derangement (lower left).
Erlandsson, "Capillary density: An important parameter in nailfold capillaroscopy," Microvascular Research, vol.
Nailfold capillaroscopy is an easy and noninvasive technique used to investigate dermal microvasculature.