capillary gel electrophoresis


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capillary gel electrophoresis

[¦kap·ə·ler·ē ¦jel i‚lek·trō·fə′rē·səs]
(analytical chemistry)
A form of capillary electrophoresis in which a polyacrylamide gel (or other polymeric material) is placed inside the capillary and separation is based on size and charge; often used to separate oligonucleotides and proteins.
References in periodicals archive ?
Here we report a quantitative PCR method, followed by separation by capillary gel electrophoresis of the fluorescently labeled amplified exons of hot spot regions of the dystrophin gene, which allowed us to detect ~99% patients (affected males and female carriers) with macrodeletions and 89% with macroduplications, and to identify small insertions or deletions in those regions.
High-resolution capillary gel electrophoresis of reducing oligosaccharides labeled with 1-aminopyrene-3,6,8-trisulfonate.
This method can easily be implemented into a minimally equipped laboratory, and the detection of the PCR products can be automated by the use of capillary gel electrophoresis. However, a technical failure in the PCR could lead to misclassification of a patient's Apo E genotype.
Prediction of migration behaviour of oligonucleotides in capillary gel electrophoresis. J Chromatogr 1992; 593:297-303.
Capillary gel electrophoresis (CGE) in molecular pathology and genetics is an ideal instrument for fast, fully automated analysis.