Carboranes


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Carboranes

 

chemical compounds composed of boron, carbon, and hydrogen atoms and having the general formula BnCm Hn+m.In carboranes, the B and C atoms are arranged at the vertices of the more or less regular polyhedron; every atom of B or C is bonded to one H atom. One of the B or C atoms in carboranes can be replaced by one atom of another element, such as phosphorus, arsenic, tin, or aluminum. The state of aggregation for carboranes changes from gaseous to solid as n increases. Carboranes and their derivatives are noted for their high thermal and chemical stability. Their properties are in many ways similar to those of aromatic hydrocarbons. Carboranes are therefore capable of undergoing various transformations related to the substitution of the H atoms located at the C or B atom.Carboranes are primarily formed by the interaction of acetylene derivatives with the corresponding boranes.

The carborane B 10C2H12 is used in the preparation of different types of polymers used in solid rocket fuels and as a thermostable coating.

REFERENCES

Mikhailov, B. M. Khimiia borovodorodov. Moscow, 1967.
Zhigach, A. F., and D. S. Stasinevich. Khimiia gidridov. Leningrad, 1969.

N. I. BEKASOVA

References in periodicals archive ?
Carborane has been found to be useful as a good inhibitor and has high lipophilicity properties which are useful for binding with the receptor binding site on the hydrophobic active site of the enzyme [42].
The ZBG would be substituted with boronic acid and carborane, part of the linker would be substituted with p-aminobenzoic acid compounds, and hydrophobic parts of cap would be substituted with organoboron compounds from the website of organoborons database (http://www.organoborons.com/) Figure 1).
Zerbetto, "In silico carborane docking to proteins and potential drug targets," Journal of Chemical Information and Modeling, vol.
In the study, Lee and his research team used carboranes to build new drugs designed to shut off a cancer cell's energy production, which is vital for the cell's survival.
With carboranes, Lee found that the drug is able to bind 10 times more powerfully.
"The reason why these drugs bind stronger to their target is because carboranes exploit a unique and very strong form of hydrogen bonding, the strongest form of interactions for drugs," Lee said.
Most of the polymers containing carborane units in the main chains are prepared from m- and p-carborane monomers.
Carborane moieties are represented by the B--H stretching band at about 2570 [cm.sup.-1], which is different from that of [B.sub.10][H.sub.14] (doublet peak: 2535 and 2588 [cm.sup.-1]) or the probable intermediate [B.sub.10][H.sub.12] x 2[CH.sub.3]CN (2520 [cm.sup.-1]).
In the ACS Nano paper, Weiss and his colleagues report enabling types of carboranes called carboranethiols to assemble into a layer attached to a gold surface through sulfur-gold bonds.
A carborane molecule is a cage of 10 boron atoms and two carbon atoms, and extra atoms can be attached to the cage.
Although the chemistry of carboranes as anions has a relatively long (ca 40 years) history, the first actual carborane-based "weighable and measurable" superacids (i.e., conjugate acids of carborane anions) were synthesized and liberated by Reed and coworkers in 2000 [7-9].
Carboranes: a new class of weakly coordinating anions for strong electrophiles, oxidants, and superacids.