Carboxyhemoglobin

(redirected from Carboxyhaemoglobin)
Also found in: Dictionary, Medical, Wikipedia.

carboxyhemoglobin

[kär¦bäk·sē¦hē·mə‚glō·bən]
(biochemistry)

Carboxyhemoglobin

 

HbCO, a compound formed by the binding of carbon monoxide (CO) to hemoglobin (Hb).

Carboxyhemoglobin solutions are bright red. Their absorption spectrum has maximums at wavelengths of 570 and 539 mμ. Carboxyhemoglobin breaks down to Hb and CO 10, 000 times more slowly than does oxyhemoglobin to Hb and O2. Therefore, when CO is present in inhaled air the oxygen is gradually displaced from the hemoglobin. Even at an atmospheric CO concentration of 0.1 percent, more than half the hemoglobin in the blood is converted to carboxyhemoglobin, interfering with the transfer of O2 from the lungs to the tissues and causing carbonmonoxide poisoning.

References in periodicals archive ?
Symptoms associated with elevated carboxyhaemoglobin levels and carbon monoxide poisoning (Watson 2010)
Validity of CO-oximetric determination of carboxyhaemoglobin in putrefying blood and body cavity fluid.
It can combine with the hemoglobin in blood to form carboxyhaemoglobin, and can therefore be lethal with prolonged exposure by preventing the flow of oxygen through the bloodstream.
Glucose-6-phosphate dehydrogenase deficiency and carboxyhaemoglobin concentrations associated with bilirubin related morbiditu and death in Nigerian infants.
healthy control subjects who did not have any comorbid diseases and smoking habitus were also enrolled to compare the differences between carboxyhaemoglobin levels A two-tailed Mann-Whitney U test with Bonferroni correction was done following a Kruskal-Wallis test for statistical purposes.
CO, a product of tobacco combustion, binds with haemoglobin (Hb) to form carboxyhaemoglobin (COHb) which deprives Hb of its oxygen-carrying capacity.
He explained that the campaign, which included a lecture highlighting the dangers of tobacco and a test that showed the level of carbon monoxide and carboxyhaemoglobin in exhaled breath, was intended to raise employees' awareness about the dangers of smoking and to show them ways and places where they could seek help to quit.
Carboxyhaemoglobin (HbCO) and methaemoglobin (MetHb) are formed after CO and haemoglobin combine (Alp et al 2004).
The increased carboxyhaemoglobin seems to contribute to the reversible decrease in TLCO.
Carboxyhaemoglobin levels were measured by spectral absorption using a Coming 2500 CO-oximeter to verify patient information on cigarette smoke intake.
Although exposure is small as compared with that experienced by mainstream smokers, passive smokers who are in the same room may show pulmonary deposition of smoke particles as well as increased blood levels of nicotine and carboxyhaemoglobin.