The newly identified virus was classified under the genus Cardiovirus
, family Picornaviradae.
To the Editor: A new member of the genus Cardiovirus
, termed Saffold virus (SAFV), was discovered recently in stool specimens and nasopharyngeal aspirate samples from patients with fever of unknown origin, respiratory symptoms, or gastroenteritis; these have been considered the first documented reports of cardiovirus
infection in humans (1-4).
Picornaviruses are currently divided into 8 genera: Enterovirus, Aphthovirus, Cardiovirus
, Hepatovirus, Parechovirus, Erbovirus, Teschovirus, and Kobuvirus (1).
To the Editor: The picornaviruses constitute a large, diverse family of positive-sense RNA viruses, which comprise 8 genera: Enterovirus, Aphthovirus, Cardiovirus
, Hepatovirus, Parechovirus, Erbovirus, Kobuvirus, and Teschovirus (1).
Picornaviruses (family Picornaviridae) are small, non-enveloped viruses with single-stranded, positive-sense genomic RNA; they are divided into 12 genera: Aphthovirus, Avihepatovirus, Cardiovirus
, Enterovirus, Erbovirus, Hepatovirus, Parechovirus, Sapelovirus, Senecavirus, Teschovirus, Tremovirus, and Kobuvirus (1).
in children with acute gastroenteritis, Beijing, China.
The cardioviruses (family Picornaviridae, genus Cardiovirus
) are pathogens of rodents and include a murine encephalomyocarditis virus and Theiler's virus and related strains (species Theilovirus), the latter serving as laboratory models of the pathogenesis of multiple sclerosis in mice (1).
The family Picornaviridae includes 12 established genera, and representatives of 5 of these have been found in humans (Enterovirus, Hepatovirus, Parechovirus, Cardiovirus
, and Kobuvirus).
To the Editor: Since 2007, a new cardiovirus
, named Saffold virus (SAFV), has been isolated from human specimens in the United States, Canada, the Netherlands, and People's Republic of China (1-4).
To the Editor: Saffold virus (SAFV) is a new human virus belonging to the genus Cardiovirus
of the family Picornaviridae (1-6).
in the family Picornaviridae was isolated and identified from fecal specimens of a child with fever of unknown origin in the United States (3).
Saffold virus, a human Theiler's-like cardiovirus
, is ubiquitous and causes infection early in life.