cephalothin

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Related to Cefalotin: cephalothin, Keflin

cephalothin

[′sef·ə·lə·thən]
(microbiology)
An antibiotic derived from the fungus Cephalosporium, resembling penicillin units in structure and activity, and effective against many gram-positive cocci that are resistant to penicillin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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We also found statistically significant (p<0.05) association between the levels of resistances to penicillin, cefalotin, cefazoline, and ceftriaxone with mupirocin, rifampicin, trimethoprim, imipenem and gentamicin antibiotics.
While it has a sensitivity of 100% to imipenem and meropenem, it has a resistance of 62.1% to cefalotin and a resistance of 48.1% to piperacillin.
aureus SNPC n s % n s % Azithromycin 44 32 72.72 46 19 41.30 Ampicillin (Amp) Amp/Sulbactam Cefazolin Cefalotin 44 39 88.63 46 38 82.60 Ceftazidime SMT + TMT 44 40 90.90 46 31 67.39 Gentamicin 44 39 88.63 46 31 67.39 Ciprofloxacin 44 39 88.63 46 34 73.91 Amikacin Ceftriaxone Meropenem Penicillin 44 8 18.18 46 5 10.86 Oxacillin 44 39 88.63 46 39 84.78 Vancomycin 44 44 100 46 46 100 Cefepime Aztreonam Erithromycin 44 32 7272 46 33 71.73 Clindamycin 44 37 84.09 46 32 69.56 Chloramphenicol 44 40 90.90 46 44 95.65 PIP + TZB Rifampin 44 44 100 46 46 100 Tobramycin Antimicrobial E.
Cefalotin and Amikacin showed the highest and lowest antibiotic resistance against gram negative bacteria respectively.
Abbreviation for antimicrobial agents: AMP, ampicillin; AMC, amoxicillin/clavulanic acid; CEF, cefalotin; ATM, aztr- eonam;CN, gentamicin; KAN, kanamycin; APR, apramycin; NE, neomycin; CIP, cip-rofloxacin; NOR, norfloxacin; EN, enrofloxacinbase; DOX, doxycycline; CH, chloramphenicol; FFC, Fl-orfenicol; B,PB, Polymyxin SXT, Trimesulf; TET, tetracycline.
On the other hand, Acinetobacter sp only showed high MIC90 against 6 anti-microbes: cefazolin, cefalotin, vancomycin, penicillin G, oxacillin and clidamycin.
isolated from human feces, of which 94.5% strains were resistant to amikacin, all were resistant to kanamycin and ciprofloxacin, 84.7% of strains were resistant to vancomycin, 1.6% strains were resistant to cefalotin, and 8.5% of strains were resistant to bacitracin.
aureus No No isolation Initial antibiotic regimen None Oxa Subsequent antibiotic None None regimen Length of hospitalization 7 15 (days) Complications None None Outcome Resolution Resolution Antimicrobial testing Susceptible Ami, Cip, Cli, Ery, Ami, Cip, Ery, Gen, Rif, Tei, Van Gen, Tei, TMP-SMX, Van Resistant TMP-SMX -- Ami, amikacin; Cep, cefalotin; Cip, ciprofloxacin; Cli, clindamycin; Ery, erythromycin; Gen, gentamicin; Oxa, oxacillin; Pen G, aqueous penicillin G; Rif, rifampin; Tei, teicoplanin; TMP-SMX, trimethoprim-sulfamethoxazole; Van, vancomycin.
aeruginosa strains were validated following the Clinical Laboratory Standards Institute (CLSI).9 The following antimicrobial agents were tested: amikacin (30 ug), ampicillin (10 ug), cefalotin (30 ug), ceftriaxone (30 ug), ciprofloxacin (5 ug), cotrimoxazole (1.25/23.75 ug), gentamicin (10 ug), tetracycline (30 ug), carbinicillin (100 ug), imipenem (10 ug), nalidixic acid (30 ug), nitroforantoin (300 ug ), norfloxacine (10 ug), cefepim (30 ug), cefdinir (30) ceftizoxime (30 ug), cefotaxime (30 ug) cefotaxime/clavulanic acid (30/10 ug), ceftazidime (30 ug), and ceftazidime/clavulanic acid (30/10 ug).
aureus growth-inhibition by all (cefalotin, enrofloxacin, erithromycin, florfenicol, gentamycin, neomycin, novobiocin, oxacyllin, penicillin, sulfa + trimethoprim and tetracycline) except penicillin.
One isolate recovered in 1998 had high-level resistance to all the drugs tested, as well as to cefalotin and fluoroquinolones (ofloxacin, ciprofloxacin, and norfloxacin); however, it was susceptible to spectinomycin, tobramycin, and gentamicin.
pneumoniae was highly susceptible to ceftriaxone (93.9%), cefalotin (96.6%), and vancomycin (96.4%).