Its proprietary drug candidate Cytolin(R) is a monoclonal antibody that binds to CD11a, a cellular antigen that is a component of the cellular adhesion molecule
37,38] The pattern of integrins, a type of cellular adhesion molecule
, expressed by basal cell carcinoma was similar to patterns expressed by the more aggressive malignant melanoma.
3], a cellular adhesion molecule
that's also a growth factor for endothelial cells.
The mechanism by which NO inhibits the expression of cellular adhesion molecule
is via inhibiting the activation of the pro-inflammatory transcription factor, NF-[kappa]B (31,103-105).
The Company's proprietary drug candidate Cytolin(R) is a monoclonal antibody that binds to CD11a, a cellular antigen that is a component of the cellular adhesion molecule
The publication overseas of our patent application for a new cellular adhesion molecule
verifies our priority for the gene," said George B.
The outcomes were FMD and markers of endothelial dysfunction, including cellular adhesion molecules
, inhibitors and promoters of fibrinolysis, adiponectin, glucose, insulin, C-reactive protein (CRP), lipids, and apolipoprotein B.
5) These contradictory results encouraged us to perform a study to determine the expression of select proto-oncogenes and cellular adhesion molecules
, with a view to defining a marker that helped identify a biologically aggressive neoplasm.
Several circulating inflammation factors such as cellular adhesion molecules
and cytokines are associated with cardiovascular disease (8,12,13).
Host defenses to extravascular infections usually elicit proinflammatory cytokines and stimulate increased expression of cellular adhesion molecules
, enhancing leukocyte adhesion.
If future studies confirm our results, cellular adhesion molecules
may be potential targets to prevent restenosis in clinical practice.
This process is mediated by cellular adhesion molecules
such as sE-selectin, a specific product of endothelial cells.