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A discrete nodular lesion of inflammatory tissue in which granulation is significant.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

References in periodicals archive ?
Radiologic features of central giant cell granuloma of the jaws.
A clinical and histomorphologic comparison of central giant cell granuloma and the giant cell minor.
The unusual features of this case include the fact that the maxillary tumor was initially diagnosed as a benign central giant cell granuloma.

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