Discovered on gastrointestinal stromal tumor 1 (DOG1) is expressed in pancreatic centroacinar
cells and in solid-pseudopapillary neoplasms: novel evidence for a histogenetic relationship.
Our results indicate that the pancreas is divided into two sections: the exocrine and endocrine portion.The exocrine portionis comprised of peripheral gland cells and centroacinar
cells; the endocrine portion consists of islet cells.
After approximately 2.5 weeks, the SOX9 positivity disappeared in most of the GATA4-positive cells; it was thought that the positivity of both the factors was almost completely limited at the postcoital 14th week and this suggested that the cells containing GATA4 were differentiated into the surrounding SOX9-positive centroacinar
In the pancreas, ductal and centroacinar
cells were intensely stained for p-mTOR, while islet and acinar cells were p-mTOR negative (Figures 1(c) and 2(b)).
Miyauchi, "Staining of pancreatic centroacinar
cells, liver bile canaliculi and testicular Leydig cells with a monoclonal antibody against adrenocortical cells," Cell & Tissue Research, vol.
This portion is comprised mainly of acinar, centroacinar
, and ductal cells.
A paracrine signaling pathway was demonstrated by Kulaksiz and Cetin (85) who detected the presence of uroguanylin and GC-C in human centroacinar
cells and the epithelial cells of pancreas ducts, but not in the islets of Langerhans.
(14) Recently, a centroacinar
cell origin has been proposed because of uniform expression of DOG-1.
Enfisema centrolobular (centroacinar
) e panlobular (panacinar)
Se le realizo una tomografia axial computarizada (TAC) sin contraste que confirmo la presencia de una masa en dicho segmento, con bordes espiculados y dimensiones maximas de 41 x 36 mm, junto a ensanchamiento hiliar izquierdo compatible con adenopatias y signos de enfisema centroacinar
. Los datos descritos sugirieron una neoformacion pulmonar (Fig.
Enzymatic secretions from the acinar cell clusters pass through ducts lined with cells (centroacinar
cells) that produce a watery secretion rich in sodium bicarbonate; pancreatic secretions thus have a basic pH to neutralize the highly acidic secretions of the stomach.